Results 41 to 50 of about 2,188,246 (287)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Partial Realization Theory and System Identification Redux
, 2017 Some twenty years ago we introduced a nonstandard matrix Riccati equation to solve the partial stochastic realization problem. In this paper we provide a new derivation of this equation in the context of system identification. This allows us to show that
Lindquist, Anders
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Optical solitary wave solutions in generalized determinant form for Kundu–Eckhaus equation
Results in Physics, 2023 The Kundu–Eckhaus (KE) equation describes the propagation of ultra-short femtosecond pulses in optical fibers. In this paper, on the basis of Hirota bilinear form of KE equation, a complex matrix is introduced into the differential relation satisfied by ...
Gui-Min Yue, Xiang-Hua Meng
doaj +1 more source
Affine Toda Field Theory in the Presence of Reflecting Boundaries [PDF]
, 1993 We show that the ``boundary crossing-unitarity equation" recently proposed by Ghoshal and Zamolodchikov is a consequence of the boundary bootstrap equation for the S-matrix and the wall-bootstrap equation.
Andreas Fring +39 more
core +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Matrix quadratic equations [PDF]
Bulletin of the Australian Mathematical Society, 1974 Matrix quadratic equations have found the most diverse applications. The present article gives a connected account of their theory, and contains some new results and new proofs of known results.
openaire +2 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Nonlinear dynamics of open quantum systems
, 2017 The evolution of a composite closed system using the integral wave equation with the kernel in the form of path integral is considered. It is supposed that a quantum particle is a subsystem of this system.
Samarin, A. Yu.
core +1 more source