Results 51 to 60 of about 3,287,874 (300)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Estimates for the Cauchy matrix of perturbed linear impulsive equation [PDF]

, 1994
Estimates for the Cauchy matrix of a perturbed linear impulsive equation are obtained for given estimates for the Cauchy matrix of the corresponding unperturbed linear impulsive ...
D. D. Bainov, P. S. Simeonov
core   +1 more source

A Robust Hermitian and Skew-Hermitian Based Multiplicative Splitting Iterative Method for the Continuous Sylvester Equation

Mathematics
For solving the continuous Sylvester equation, a class of Hermitian and skew-Hermitian based multiplicative splitting iteration methods is presented. We consider two symmetric positive definite splittings for each coefficient matrix of the continuous ...
Mohammad Khorsand Zak, Abbas Abbaszadeh Shahri   +1 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Optical solitary wave solutions in generalized determinant form for Kundu–Eckhaus equation

Results in Physics, 2023
The Kundu–Eckhaus (KE) equation describes the propagation of ultra-short femtosecond pulses in optical fibers. In this paper, on the basis of Hirota bilinear form of KE equation, a complex matrix is introduced into the differential relation satisfied by ...
Gui-Min Yue, Xiang-Hua Meng
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Some Rank Formulas for the Yang-Baxter Matrix Equation

, 2021
Let A be an arbitrary square matrix, then equation AXA =XAX with unknown X is called Yang-Baxter matrix equation. It is difficult to find all the solutions of this equation for any given A.
Yonghong SHEN, Maolin LIANG, Lifang DAI
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Special solutions of matrix Gellerstedt equation

Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2011
Fundamental solutions for the Gellerstedt equation and its generalization were obtained in the distribution space using the method applied by I. M. Gelfand and J. Barros-Neto to the studying the Tricomi equation. The degenerating system of the mixed-type
Elena A Kozlova
doaj   +3 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source