Results 71 to 80 of about 419,229 (311)

Legendre collocation method and its convergence analysis for the numerical solutions of the conductor-like screening model for real solvents integral equation

Bulletin of Computational Applied Mathematics, 2016
In this paper, a reliable algorithm for solving the nonlinear Hammerstein integral equation arising from chemical phenomenon is presented. The conductor-like screening model for real solvents (COSMO-RS) integral equation will be solved by the shifted ...
Esmail Hesameddini, Mehdi Shahbazi
doaj  

A Robust Hermitian and Skew-Hermitian Based Multiplicative Splitting Iterative Method for the Continuous Sylvester Equation

Mathematics
For solving the continuous Sylvester equation, a class of Hermitian and skew-Hermitian based multiplicative splitting iteration methods is presented. We consider two symmetric positive definite splittings for each coefficient matrix of the continuous ...
Mohammad Khorsand Zak, Abbas Abbaszadeh Shahri   +1 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Precision matrix estimation using penalized Generalized Sylvester matrix equation

, 2022
Estimating a precision matrix is an important problem in several research fields when dealing with large-scale data. Under high-dimensional settings, one of the most popular approaches is optimizing a Lasso or ℓ1 norm penalized objective loss function ...
Avagyan, Vahe
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Spectral collocation method for convection-diffusion equation

Demonstratio Mathematica
Spectral collocation method, named linear barycentric rational interpolation collocation method (LBRICM), for convection-diffusion (C-D) equation with constant coefficient is considered.
Li Jin, Cheng Yongling
doaj   +1 more source

Kaczmarz-Type Methods for Solving Matrix Equation AXB = C

Axioms
This paper proposes a class of randomized Kaczmarz and Gauss–Seidel-type methods for solving the matrix equation AXB=C, where the matrices A and B may be either full-rank or rank deficient and the system may be consistent or inconsistent. These iterative
Wei Zheng, Lili Xing, Wendi Bao, Weiguo Li   +3 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

The Re-nonnegative definite solutions to the matrix equation $AXB=C$ [PDF]

, 1998
summary:An $n\times n$ complex matrix $A$ is called Re-nonnegative definite (Re-nnd) if the real part of $x^{\ast } Ax$ is nonnegative for every complex $n$-vector $x$. In this paper criteria for a partitioned matrix to be Re-nnd are given.
Yang, Changlan, Wang, Qingwen
core