Results 91 to 100 of about 419,229 (311)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Robust Pole Assignment via Sylvester Equation Based State Feedback Parametrization

, 2000
By using a Sylvester equation based parametrization, the minimum norm robust pole assignment problem for linear time-invariant systems is formulated as an unconstrained minimization problem for a suitably chosen cost function.
Varga, Andras
core  

Discrete Tracy--Widom operators. [PDF]

, 2009
Integrable operators arise in random matrix theory, where they describe the asymptotic eigenvalue distribution of large self-adjoint random matrices from the generalized unitary ensembles.
McCafferty, Andrew, Blower, Gordon
core  

Solution for Matrix Equation AX-YB=C

, 2019
The inverse of a matrix A can only exist if A is nonsingular. This is an important theorem in linear algebra, one learned in an introductory course. In recent years, needs have been felt in numerous areas of applied mathematics for some kind of inverse ...
., Yanita, Bahri, Susila, Cahyadi, Nadia
core   +1 more source

A robust zeroing neural network and its applications to dynamic complex matrix equation solving and robotic manipulator trajectory tracking. [PDF]

Front Neurorobot, 2022
Jin J, Zhao L, Chen L, Chen W.
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Density matrix form of Gross-Pitaevskii equation

, 2014
We consider the generalized pure state density matrix which depends on different time moments. The evolution equation for this density matrix is obtained in case where the density matrix corresponds to the solutions of Gross-Pitaevskii ...
V. N. Chernega, O. V. Man’ko, Manko, Olga V., Chernega, Vladimir N., V. I. Man’ko, Manko, Vladimir I.   +5 more
core   +1 more source

Variable s-step CGNR method for solving the matrix equation AXB = C arising in image processing

Mathematical Modelling and Analysis
The matrix equation $ {AXB} = {C}$ is widely utilized in signal and image processing. In this paper, we present a variable s-step algorithm based on the CGNR method for solving this matrix equation by employing normalization techniques.
Hojjatollah Shokri Kaveh, Masoud Hajarian   +1 more
doaj   +1 more source

Nonrecursive solution for the discrete algebraic Riccati equation and X + A*X-1A=L

Open Mathematics, 2015
In this paper, we present two new algebraic algorithms for the solution of the discrete algebraic Riccati equation. The first algorithm requires the nonsingularity of the transition matrix and is based on the solution of a standard eigenvalue problem for
Adam Maria, Assimakis Nicholas
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source