Results 41 to 50 of about 1,484,501 (262)

Lysosomal Function Impacts the Skeletal Muscle Extracellular Matrix

open access: yesJournal of Developmental Biology, 2021
Muscle development and homeostasis are critical for normal muscle function. A key aspect of muscle physiology during development, growth, and homeostasis is modulation of protein turnover, the balance between synthesis and degradation of muscle proteins.
Elizabeth C. Coffey   +4 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Matrix model partition function by a single constraint

open access: yesEuropean Physical Journal C: Particles and Fields, 2021
In the recent study of Virasoro action on characters, we discovered that it gets especially simple for peculiar linear combinations of the Virasoro operators: particular harmonics of $${\hat{w}}$$ w ^ -operators.
A. Mironov   +3 more
doaj   +1 more source

Modified Ranking Function to Compute Fuzzy Matrix Games

open access: yesIbn Al-Haitham Journal for Pure and Applied Sciences, 2022
Game theory problems (GTP) frequently occur in Economy, Business Studies, Sociology, Political Science, Military Activities, and so on are some of the subjects covered.
Rasha Jalal Mitlif
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Classical special functions of matrix arguments

open access: yesSistemnì Doslìdženâ ta Informacìjnì Tehnologìï
This article focuses on a few of the most commonly used special functions and their key properties and defines an analytical approach to building their matrix-variate counterparts.
Dmytro Shutiak   +3 more
doaj   +1 more source

Approximate Factorization for One Class of Second-Order Matrix Functions [PDF]

open access: yesУчёные записки Казанского университета: Серия Физико-математические науки, 2016
Approximate factorization of Holder matrix function on a simple smooth closed contour has been defined. Components for one class of the 2×2 matrix function have been approximated by polynomials in z and 1/ z.
S.N. Kiyasov
doaj  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Investigation of Fractional Calculus for Extended Wright Hypergeometric Matrix Functions

open access: yesAbstract and Applied Analysis, 2023
Throughout this paper, we will present a new extension of the Wright hypergeometric matrix function by employing the extended Pochhammer matrix symbol. First, we present the extended hypergeometric matrix function and express certain integral equations ...
Mohamed Niyaz   +2 more
doaj   +1 more source

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