Results 91 to 100 of about 2,686,420 (304)

Pay32p of the Yeast Yarrowia lipolytica Is an Intraperoxisomal Component of the Matrix Protein Translocation Machinery [PDF]

open access: yes, 1995
Pay mutants of the yeast Yarrowia lipolytica fail to assemble functional peroxisomes. One mutant strain, pay32-1, has abnormally small peroxisomes that are often found in clusters surrounded by membranous material.
Rachubinski, Richard A.   +15 more
core   +2 more sources

A Novel 6-DOF Passive Vibration Isolation System for Aviation Optoelectronic Turret and Its Impact Analysis on Optical Systems Imaging Performance

open access: yesAerospace
In recent years, with the rapid development of the unmanned aerial vehicle industry, aviation optoelectronic turrets have been widely applied in fields such as terrain exploration, disaster prevention and mitigation, and national defense.
Wenxin Shi   +7 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Single-Crystal Matrix Isolation of Biopolymers

open access: yes, 2016
Single-Crystal Matrix Isolation of ...
Phil Savickas (3001539)   +7 more
core   +1 more source

Pancreatic Islet Basement Membrane Loss and Remodeling after Mouse Islet Isolation and Transplantation: Impact for Allograft Rejection

open access: yesCell Transplantation, 2014
The isolation of islets by collagenase digestion can cause damage and impact the efficiency of islet engraftment and function. In this study, we assessed the basement membranes (BMs) of mouse pancreatic islets as a molecular biomarker for islet integrity,
H. F. Irving-Rodgers   +5 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Problem of the gyroscopic stabilizer damping [PDF]

open access: yesApplied and Computational Mechanics, 2009
The gyroscopic stabilization of the vibro-isolation system of an ambulance couch is analyzed. This paper follows several previous papers, which concern the derivation of the complete system of appropriate differential equations and some analyses were ...
Šklíba J.
doaj  

The Interplay and Synergism of Experiment and Quantum Chemistry in Research on Reactive Intermediates

open access: yesCHIMIA, 2005
Three examples from the work of the author's research group on reactive intermediates are used to illustrate how fruitful interaction between experimental and computational chemistry may lead to the solution of problems that neither of the two ...
Thomas Bally
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Observer-based controller design for a vibration isolation stage having hybrid electromagnets

open access: yesJournal of Low Frequency Noise, Vibration and Active Control, 2018
Vibration isolation systems based on hybrid electromagnets, consisting of electromagnet and permanent magnet, have a potential usage in many industrial areas, such as clean room design, transportation, semiconductor manufacturing, suspension systems, and
Barış Can Yalçın   +2 more
doaj   +1 more source

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