Results 81 to 90 of about 429,621 (305)

New computational approach for the design of fault detection and isolation filters

, 2003
We propose a numerically reliable computational approach for the design of residual generators for fault detection and isolation filters. The new approach is based on computing solutions of least dynamical orders of linear equations with rational matrix ...
Varga, Andras
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Descriptor system techniques in solving H2/H-infinity optimal fault detection and isolation problems.

, 2012
This chapter illustrates the effectiveness of descriptor systems based algorithms in solving H2/H-infinity optimal fault detection and isolation problems.
Varga, A
core  

A Novel 6-DOF Passive Vibration Isolation System for Aviation Optoelectronic Turret and Its Impact Analysis on Optical Systems Imaging Performance

Aerospace
In recent years, with the rapid development of the unmanned aerial vehicle industry, aviation optoelectronic turrets have been widely applied in fields such as terrain exploration, disaster prevention and mitigation, and national defense.
Wenxin Shi, Lei Li, Haishuang Fu, Chen Shui, Yijian Wang, Dejiang Wang, Xiantao Li, Bao Zhang   +7 more
doaj   +1 more source

Pancreatic Islet Basement Membrane Loss and Remodeling after Mouse Islet Isolation and Transplantation: Impact for Allograft Rejection

Cell Transplantation, 2014
The isolation of islets by collagenase digestion can cause damage and impact the efficiency of islet engraftment and function. In this study, we assessed the basement membranes (BMs) of mouse pancreatic islets as a molecular biomarker for islet integrity,
H. F. Irving-Rodgers, F. J. Choong, K. Hummitzsch, C. R. Parish, R. J. Rodgers, C. J. Simeonovic   +5 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Descriptor system techniques in solving H2/infinity-optimal fault detection and isolation problems

, 2012
This chapter illustrates the effectiveness of descriptor systems based algorithms in solving H2/infinity-optimal fault detection and isolation problems.
Varga, Andreas
core  

Isolation and Culture of Murine Hepatic Stellate Cells

Bio-Protocol, 2019
Hepatic stellate cells (HSCs), alternatively known as liver pericytes, can differentiate into myofibroblasts and secrete extra-cellular matrix components, thereby promoting wound healing and fibrosis.
Rucha Modak, Dietmar Zaiss
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Successive translocation into and out of the mitochondrial matrix [PDF]

, 1987
We investigated the import and sorting pathways of cytochrome b2 and cytochrome c1, which are functionally located in the intermembrane space of mitochondria.
Ostermann, Joachim, Hartl, Franz-Ulrich, Neupert, Walter, Guiard, Bernard   +3 more
core   +1 more source