Results 41 to 50 of about 429,621 (305)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

A sustainable approach on the utilisation of COVID-19 plastic based isolation gowns in structural concrete

Case Studies in Construction Materials, 2022
Single-use isolation gowns have become an important practice across medical centres, testing sites, and emergency rooms since the onset of the Coronavirus pandemic; within the later months of 2019. Although reusable isolation gowns have proved beneficial,
Shannon Kilmartin-Lynch, Rajeev Roychand, Mohammad Saberian, Jie Li, Guomin Zhang, Sujeeva Setunge   +5 more
doaj   +1 more source

Thermochemistry and photochemistry of spiroketals derived from indan-2-one: Stepwise processes versus coarctate fragmentations

Beilstein Journal of Organic Chemistry, 2013
Coarctate reactions are defined as reactions that include atoms at which two bonds are made and two bonds are broken simultaneously. In the pursuit of the discovery of new coarctate reactions we investigate the fragmentation reactions of cyclic ketals ...
Götz Bucher, Gernot Heitmann, Rainer Herges   +2 more
doaj   +1 more source

Computing the Isolated Roots by Matrix Methods

Journal of Symbolic Computation, 1998
One approach to compute the roots of a zero-dimensional polynomial system is based on resultant formulations and can be performed with floating point arithmetic. In this paper, reinvestigating the resultant approach from the linear algebra point of view the author handles the problem of genericity and presents a new algorithm for computing the isolated
openaire   +2 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

A study of the variability in the molecular structure of the human pancreas with age and its effect on islet isolation and transplantation outcomes: Impact of donor age on the structure and enzymatic digestion of the pancreatic extrecellular matrix during human islet isolation

, 2020
Pancreatic islet transplantation is a minimally invasive treatment that has the potential to reverse Type 1 Diabetes Mellitus in selected patients. Islets of Langerhans are isolated (extracted) from the pancreatic exocrine tissue using a collagenase and ...
Spiers, Rebecca
core   +1 more source

Pay32p of the Yeast Yarrowia lipolytica Is an Intraperoxisomal Component of the Matrix Protein Translocation Machinery [PDF]

, 1995
Pay mutants of the yeast Yarrowia lipolytica fail to assemble functional peroxisomes. One mutant strain, pay32-1, has abnormally small peroxisomes that are often found in clusters surrounded by membranous material.
Rachubinski, Richard A., Szilard, Rachel K., Rachubinski, Richard A.,, Titorenko, Vladimir I.,, V I Titorenko, R A Rachubinski, Titorenko, Vladimir I., Rachel K. Szilard, M Veenhuis, Veenhuis, Marten,, R K Szilard, Szilard, Rachel K.,, Richard A. Rachubinski, Marten Veenhuis, Veenhuis, Marten, Vladimir I. Titorenko   +15 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Solid phase extraction for removal of matrix effects in lipophilic marine toxin analysis by liquid chromatography-tandem mass spectrometry [PDF]

, 2009
The potential of solid phase extraction (SPE) clean-up has been assessed to reduce matrix effects (signal suppression or enhancement) in the liquid chromatography-tandem mass spectrometry (LC¿MS/MS) analysis of lipophilic marine toxins.
Boer, J., de, Bire, Ronel, Bire, R., de Boer, J., de Boer, J.; id_orcid, Jacob de Boer, Boer, J. de, Mulder, Patrick P. J., McElhinney, A. M., Hess, Philipp, McElhinney, M., Philipp Hess, Gerssen, A., Mairead A. McElhinney, Gerssen, Arjen, Ronel Bire, Arjen Gerssen, Bire, L., de Boer, Jacob, Patrick P. J. Mulder, Mulder, P.P.J., Hess, P., McElhinney, Mairead A.   +22 more
core   +1 more source

A new test vector optimization method for failure isolation

Dianzi Jishu Yingyong, 2018
In order to improve the fault diagnosis efficiency and shorten the fault isolation time based on the testability modeling, a test vector optimization method is proposed. Aiming at the exact detection and isolation requirements of each failure mode in the
Jiang Jueyi, Li Fan, Li Jianhong
doaj   +1 more source