Results 31 to 40 of about 1,579,901 (232)

Bioinformatic mapping of a more precise Aspergillus niger degradome

open access: yesScientific Reports, 2021
Aspergillus niger has the ability to produce a large variety of proteases, which are of particular importance for protein digestion, intracellular protein turnover, cell signaling, flavour development, extracellular matrix remodeling and microbial ...
Zixing Dong   +2 more
doaj   +1 more source

Prolonged Cadmium Exposure Alters Migration Dynamics and Increases Heterogeneity of Human Uterine Fibroid Cells—Insights from Time Lapse Analysis

open access: yesBiomedicines, 2022
Cadmium (Cd) is one of the most prevalent environmental heavy metal contaminants and is considered an endocrine disruptor and carcinogen. In women with uterine fibroids, there is a correlation between blood Cd levels and fibroid tumor size. In this study,
Yitang Yan   +6 more
doaj   +1 more source

JNK suppression is essential for 17β-Estradiol inhibits prostaglandin E2-Induced uPA and MMP-9 expressions and cell migration in human LoVo colon cancer cells

open access: yesJournal of Biomedical Science, 2011
Background Epidemiological studies demonstrate that the incidence and mortality rates of colorectal cancer in women are lower than in men. However, it is unknown if 17β-estradiol treatment is sufficient to inhibit prostaglandin E2 (PGE2)-induced cellular
Chen Wei-Kung   +9 more
doaj   +1 more source

MMP14 (matrix metallopeptidase 14 (membrane-inserted)) [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on MMP14 (matrix metallopeptidase 14 (membrane-inserted)), with data on DNA, on the protein encoded, and where the gene is implicated.
Kuscu, C, Evensen, N, Cao, J
openaire   +2 more sources

MMP15 (matrix metallopeptidase 15 (membrane-inserted)) [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2013
Review on MMP15 (matrix metallopeptidase 15 (membrane-inserted)), with data on DNA, on the protein encoded, and where the gene is implicated.
Ito, E, Yana, I, Matsuura, N
openaire   +2 more sources

A novel mutation in the matrix metallopeptidase 2 coding gene associated with intrafamilial variability of multicentric osteolysis, nodulosis, and arthropathy

open access: yesMolecular Genetics & Genomic Medicine, 2019
Background MONA, which stands for a spectrum of Multicentric Osteolysis, subcutaneous Nodulosis, and Athropathia, is an ultra rare autosomal recessive disorder caused by mutations in the matrix metallopeptidase 2 (MMP2) gene. To date only 44 individuals,
Liisa Kröger   +6 more
doaj   +1 more source

Gallic acid regulates immune response in a mouse model of rheumatoid arthritis

open access: yesImmunity, Inflammation and Disease, 2023
Introduction Previous studies revealed that gallic acid (GA) exerts anti‐inflammation and immuno‐regulatory properties. This study aims to explore the pharmacological activities of GA in collagen‐induced arthritis (CIA) mouse model.
Siqin Liu, Jiajia Li, Le‐heng Feng
doaj   +1 more source

Profile of Expression of Genes Encoding Matrix Metallopeptidase 9 (MMP9), Matrix Metallopeptidase 28 (MMP28) and TIMP Metallopeptidase Inhibitor 1 (TIMP1) in Colorectal Cancer: Assessment of the Role in Diagnosis and Prognostication [PDF]

open access: yesMedical Science Monitor, 2017
BACKGROUND Studies on the pathomechanism of colorectal cancer (CRC) expansion indicate a significant role of metalloproteinases and their inhibitors in the extracellular matrix. The results of the analysis of a profile of transcriptional activity of genes encoding metalloproteinases were the basis of the hypothesis indicating changes in the expression ...
Lorenc, Zbigniew   +6 more
openaire   +3 more sources

Effect of nanoparticles on the expression and activity of matrix metalloproteinases

open access: yesNanotechnology Reviews, 2018
Matrix metallopeptidases, commonly known as matrix metalloproteinases (MMPs), are a group of proteolytic enzymes whose main function is the remodeling of the extracellular matrix. Changes in the activity of these enzymes are observed in many pathological
Matysiak-Kucharek Magdalena   +4 more
doaj   +1 more source

Promoter polymorphisms in matrix metallopeptidase 1 and risk of cutaneous melanoma [PDF]

open access: yesEuropean Journal of Cancer, 2011
Matrix metallopeptidase 1 (MMP1) is one of the interstitial collagens in the extracellular matrix metalloproteinase family and involved in tumour behaviours. However, there is no report on the role of genetic variation in MMP1 in risk of cutaneous melanoma (CM).
Li-E, Wang   +8 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy