Results 21 to 30 of about 1,579,901 (232)
M-MATRIX-WP6.M1 - "DASHBOARDS OPERATIONAL WITHIN THE PILOT PARTICIPATING AGENCIES"
, 2022 M-MATRIX-WP6.M1 - “Dashboards operational within the pilot participating agencies” Milestone report for M1 of MATRIX ...
MATRIX
core +1 more source
PLoS ONE, 2020 Despite increasing research on the gut-skin axis, there is a lack of comprehensive studies on the improvement of skin health through the regulation of the intestinal condition in humans.
Bora Nam +9 more
doaj +1 more source
Cleavage‐Responsive Biofactory T Cells Suppress Infectious Diseases‐Associated Hypercytokinemia
Advanced Science, 2022 Severe infectious diseases, such as coronavirus disease 2019 (COVID‐19), can induce hypercytokinemia and multiple organ failure. In spite of the growing demand for peptide therapeutics against infectious diseases, current small molecule‐based strategies ...
Hyelim Kim +12 more
doaj +1 more source
Role of Angiopoietins in Development of Cancer and Neoplasia Associated with Viral Infection
Cells, 2020 Angiopoietin/tyrosine protein kinase receptor Tie-2 signaling in endothelial cells plays an essential role in angiogenesis and wound healing. Angiopoietin-1 (Ang-1) is crucial for blood vessel maturation while angiopoietin-2 (Ang-2), in collaboration ...
Xiaolan Yu, Fengchun Ye
doaj +1 more source
Molecular Therapy: Nucleic Acids, 2023 The cell origin-specific payloads within extracellular vesicles (EVs) mediate therapeutic bioactivity for a wide variety of stem cell types. In this study, we profiled the microRNA (miRNA) and protein cargos found within EVs produced by three clinical ...
Ramana Vaka +6 more
doaj +1 more source
Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression
Hepatology, EarlyView., 2022 Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández +18 more
wiley +1 more source
Genome-wide analysis using exon arrays demonstrates an important role for expression of extra-cellular matrix, fibrotic control and tissue remodelling genes in Dupuytren's disease. [PDF]
PLoS ONE, 2013 Dupuytren's disease (DD) is a classic example of pathological fibrosis which results in a debilitating disorder affecting a large sector of the human population.
Helen B Forrester +5 more
doaj +1 more source
Precision Medicine Approaches to Prevent Gastric Cancer
Gut and Liver, 2021 Gastric cancer remains one of the most common causes of cancer-related death worldwide, although the incidence is declining gradually. The primary risk factor for gastric cancer is Helicobacter pylori infection.
Juntaro Matsuzaki +2 more
doaj +1 more source
Hepatology, EarlyView., 2022 CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli +13 more
wiley +1 more source
, 2018 Metallopeptidases are a family of proteins with domains that remain highly conserved throughout evolution. These hydrolases require divalent metal cation(s) to activate the water molecule in order to carry out their catalytic action on peptide bonds by ...
Sandie Escotte-Binet +13 more
core +2 more sources