Results 141 to 150 of about 143,801 (262)

Characterization of a cis-regulatory element upstream of matrix metalloproteinase-9. [PDF]

open access: yesSci Rep
Rangaraj A   +5 more
europepmc   +1 more source

Tissue‐Specific and Spatially Dependent Metabolic Signatures Perturbed by Injury in Male and Female Mice

open access: yesArthritis &Rheumatology, EarlyView.
Objective Osteoarthritis, the leading cause of disability worldwide, disproportionately affects women, yet sex remains an overlooked determinant. This disparity stems from sex‐specific differences in injury susceptibility—a major risk factor for disease.
Hope D. Welhaven   +6 more
wiley   +1 more source

The role and mechanisms of matrix metalloproteinase-9 in peripheral neuropathic pain. [PDF]

open access: yesFront Mol Neurosci
Jia SY   +5 more
europepmc   +1 more source

Arthroscopic Assisted Turf Toe Reconstruction With Knotless Suture Anchors and Suture Tape Augmentation

open access: yesArthroscopy Techniques, EarlyView.
Abstract Turf toe is a hallux metatarsophalangeal joint (MTPJ) injury seen in sports like football and soccer where the foot experiences axial load while fixed to the ground with the great toe hyperextended at the MTPJ. Depending on severity, turf toe can be quite devastating in athletes and can require operative intervention.
Nicholas K. Pappa   +3 more
wiley   +1 more source

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum   +5 more
wiley   +1 more source

Purification of Advanced Therapeutics by Flow‐Through Pseudo‐Affinity Chromatography: Bi‐Specific mABs, Fc Fusion Proteins, and Adeno‐Associated Viruses

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Modern biopharmaceutical manufacturing requires purification platforms capable of processing structurally and functionally diverse products while addressing the challenge of removing persistent and high‐risk host cell proteins (HCPs).
Wenning Chu   +23 more
wiley   +1 more source

2D copper nanozyme patches facilitate bone regeneration via interfacial modulation of osteoclast‐osteoblast dynamics

open access: yesBMEMat, EarlyView.
This study develops a nano‐enzyme patch (ezPatch) targeting bone interfaces. Utilizing ligand‐to‐metal charge transfer (LMCT) catalysis and bone‐targeting ligands on copper nanosheets, ezPatch simultaneously scavenges reactive oxygen species (ROS) and generates oxygen in situ at bone‐losing sites.
Yi Chen   +12 more
wiley   +1 more source

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