Results 11 to 20 of about 2,395,043 (357)

Integrin α2β1 Expression Regulates Matrix Metalloproteinase-1-Dependent Bronchial Epithelial Repair in Pulmonary Tuberculosis [PDF]

Frontiers in Immunology, 2018
Pulmonary tuberculosis (TB) is caused by inhalation of Mycobacterium tuberculosis, which damages the bronchial epithelial barrier to establish local infection.
Sara Brilha, Sara Brilha, Deborah L. W. Chong, Akif A. Khawaja, Catherine W. M. Ong, Catherine W. M. Ong, Naomi J. Guppy, Joanna C. Porter, Jon S. Friedland   +8 more
doaj   +8 more sources

The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) family [PDF]

Genome Biology, 2015
The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) enzymes are secreted, multi-domain matrix-associated zinc metalloendopeptidases that have diverse roles in tissue morphogenesis and patho-physiological remodeling, in ...
A Colige, A Didangelos, A Luque, A Moncada-Pazos, A Noel, A Tan Ide, AC Jonsson-Rylander, AC Nicholson, AJ Fosang, B Joe, BH Koo, BH Koo, BV Nusgens, C Casal, C Esselens, C Gendron, C Kintakas, C Lopez-Otin, C Ricciardelli, CB Kern, CG Viloria, CH Mjaatvedt, CJ Liu, CJ Liu, CL Jacobi, CM Dancevic, CN Brocker, CR Flannery, D Wagsater, DL Russell, DL Silver, DR Edwards, DR McCulloch, DT Jones, Dylan R Edwards, EA Lin, EC Arner, ED Karagiannis, EM Majerus, F Guo, F Vazquez, FG Brunet, FX Gomis-Ruth, FX Gomis-Ruth, G Gao, G Gao, G Hashimoto, G Murphy, GC Choi, GE Lind, GG Levy, GJ Wayne, Grant N Wheeler, H Enomoto, H Jin, H Stanton, H Stanton, HL Lung, HM Brown, I Abbaszade, I Peluso, Ines Desanlis, J Dubail, J Dubail, J Felsenstein, J Hofsteenge, J Huxley-Jones, J Huxley-Jones, J Morales, JA Pyun, JC Adams, JC Rodriguez-Manzaneque, JC Rodriguez-Manzaneque, JC Rodriguez-Manzaneque, JD Sandy, JM Longpre, K Demircan, K Fujikawa, K Gopalakrishnan, K Kuno, K Kuno, K Stankunas, K Tamura, K Yamamoto, K Yamamoto, L Angerer, L Faivre, L Mittaz, L Mosyak, L Troeberg, L Troeberg, L Troeberg, L Wagstaff, LA Collins-Racie, LE Dupuis, LM Ricketts, M Cudic, M Hour El, M Kashiwagi, M Krampert, M Llamazares, MA Aldahmesh, MD Tortorella, MN Vankemmelbeke, N Dagoneau, N Hattori, N Rocks, N Rocks, N Stupka, NH Lim, NV Lee, NV Lee, P Wang, PH Lo, PJ Koshy, PS Chockalingam, R Kelwick, RC Salter, RH Song, Richard Kelwick, RL Robker, RP Somerville, RP Somerville, RS Patel, S Abdul-Majeed, S Gerhardt, S Kumar, S Kumar, S Nandadasa, S Porter, S Porter, SS Apte, SS Glasson, T Fontanil, T Shindo, TN Wight, U Auf Dem Keller, W Du, W Zeng, WE Kutz, WM Wang, X Lu, X Pu, XL Zheng, YJ Liu, YP Hsu   +145 more
core   +2 more sources

Inhibitory Antibodies Designed for Matrix Metalloproteinase Modulation [PDF]

Molecules, 2019
The family of matrix metalloproteinases (MMPs) consists of a set of biological targets that are involved in a multitude of severe pathogenic events such as different forms of cancers or arthritis.
Thomas Fischer, Rainer Riedl
doaj   +3 more sources

The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family.

Proceedings of the National Academy of Sciences of the United States of America, 1990
Harold E. Van Wart, Henning Birkedal‐Hansen   +1 more
openalex   +2 more sources

The Role of Matrix Metalloproteinase in Inflammation with a Focus on Infectious Diseases

International Journal of Molecular Sciences, 2022
Matrix metalloproteinases (MMPs) are involved in extracellular matrix remodeling through the degradation of extracellular matrix components and are also involved in the inflammatory response by regulating the pro-inflammatory cytokines TNF-α and IL-1β ...
H. Lee, Woo Joo Kim
semanticscholar   +1 more source

The role of MMP-2 and MMP-9 in the metastasis and development of hypopharyngeal carcinoma

Brazilian Journal of Otorhinolaryngology, 2021
Introduction: The role of matrix metalloproteinase-2 and 9 in the metastasis and development of hypopharyngeal carcinoma has not been clarified. Objectives: To observe the relationship between matrix metalloproteinase-2, matrix metalloproteinase-9 and ...
Zhe Song, Junfu Wang, Qinghong Su, Meng Luan, Xuemei Chen, Xiaoqun Xu   +5 more
doaj   +1 more source

Matrix Metalloproteinase 3: A Promoting and Destabilizing Factor in the Pathogenesis of Disease and Cell Differentiation

Frontiers in Physiology, 2021
Cells must alter their expression profiles and morphological characteristics but also reshape the extracellular matrix (ECM) to fulfill their functions throughout their lifespan.
Jiang-Tao Wan, Guowei Zhang, Xin Li, X. Qiu, Jun Ouyang, J. Dai, Shaoxiong Min   +6 more
semanticscholar   +1 more source

Identification of a novel role for matrix metalloproteinase-3 in the modulation of B cell responses in multiple sclerosis

Frontiers in Immunology, 2022
There has been a growing interest in the presence and role of B cell aggregates within the central nervous system of multiple sclerosis patients. However, very little is known about the expression profile of molecules associated with these aggregates and
Rittika Chunder, Rittika Chunder, Verena Schropp, Verena Schropp, Samir Jabari, Manuel Marzin, Sandra Amor, Stefanie Kuerten, Stefanie Kuerten   +8 more
doaj   +1 more source

Regulation of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 in Abdominal Aortic Aneurysm

Cardiology Discovery, 2023
Abdominal aortic aneurysm (AAA) is a degenerative disease characterized by destruction and progressive expansion of the abdominal aortic wall. An AAA is typically defined as an enlargement of the abdominal aorta with diameter ≥3 cm or ≥50% greater than ...
Shuo Wang, Dan Liu, Xiaolin Zhang, Xiaoxiang Tian   +3 more
doaj   +1 more source

The Role of Matrix Metalloproteinase-9 in Atherosclerotic Plaque Instability

Mediators of Inflammation, 2020
Matrix metalloproteinase-9 (MMP-9) belongs to the MMP family and has been widely investigated. Excessive MMP-9 expression can enhance extracellular matrix degradation and promote plaque instability.
Tiewei Li, Xiaojuan Li, Yichuan Feng, Geng Dong, Yuewu Wang, Junmei Yang   +5 more
semanticscholar   +1 more source