Results 11 to 20 of about 2,315,187 (340)
The relationship between metastasis and mmp-9 in sheep with pulmonary adenocarcinomas [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2022 Th is study aimed to evaluate the role of Matrix Metalloproteinase-9 in the metastasis of ovine pulmonary adenocarcinoma cases by immunohistochemical methods.
Emin KARAKURT +5 more
doaj +1 more source
Current Medicinal Chemistry, 2010 Matrix metalloproteinases (MMPs), also known as matrixins, belong to a group of zinc-dependent proteins, which are thought to play a central role in the breakdown of extracellular matrix. Collagen, elastin, gelatin and casein are major components cleaved by MMPs.
O, Zitka +7 more
openaire +4 more sources
Архивъ внутренней медицины, 2020 The aim of the research. To assess the influence of polymorphisms of the matrix metalloproteinase genes — 2 (rs2285053), — 3 (rs3025058), and — 13 (rs2252070) on the development of coronary atherosclerosis in patients with primary osteoarthritis ...
O. O. Portyannikova +3 more
doaj +1 more source
Pharmacological Reviews, 2022 The first matrix metalloproteinase (MMP) was discovered in 1962 from the tail of a tadpole by its ability to degrade collagen. As their name suggests, matrix metalloproteinases are proteases capable of remodeling the extracellular matrix.
Luiz G. N. de Almeida +7 more
semanticscholar +1 more source
The Rebirth of Matrix Metalloproteinase Inhibitors: Moving Beyond the Dogma
Cells, 2019 The pursuit of matrix metalloproteinase (MMP) inhibitors began in earnest over three decades ago. Initial clinical trials were disappointing, resulting in a negative view of MMPs as therapeutic targets.
G. Fields
semanticscholar +1 more source
Tumor Biology, 2017 The aim of this study was to correlate matrix metalloproteinase-2 and matrix metalloproteinase-9 expression with the clinicopathological features and outcome of patients with early gastric cancer and to clinically elucidate more information on the role ...
Zhihua Yao +11 more
doaj +1 more source
Protective Role of Matrix Metalloproteinase-2 in Allergic Bronchial Asthma
Frontiers in Immunology, 2019 Inflammation, reversible obstruction, and hyperresponsiveness of the airways are characteristic findings of bronchial asthma. Several evidence has demonstrated the involvement of matrix metalloproteinase-2 in allergic airway inflammation.
Yoshinori Takahashi +17 more
doaj +1 more source
Leptin and Pro-Inflammatory Stimuli Synergistically Upregulate MMP-1 and MMP-3 Secretion in Human Gingival Fibroblasts. [PDF]
PLoS ONE, 2016 Gingival fibroblast-mediated extracellular matrix remodelling is implicated in the pathogenesis of periodontitis, yet the stimuli that regulate this response are not fully understood.
Rachel C Williams +5 more
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Matrix Metalloproteinase in Abdominal Aortic Aneurysm and Aortic Dissection
Pharmaceuticals, 2019 Abdominal Aortic Aneurysm (AAA) affects 4–5% of men over 65, and Aortic Dissection (AD) is a life-threatening aortic pathology associated with high morbidity and mortality.
E. M. Maguire +4 more
semanticscholar +1 more source
Клінічна хірургія, 2022 Objective. To improve the results of treatment in patients, suffering insufficiency of sutures of intestinal anastomoses, using analysis of rate in the genes polymorphous variants of the matrix metalloproteinase Type 2 (C-1306 →T) and the tissue ...
O. Yu. Usenko, Ya. Yu. Voitiv
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