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Matrix metalloproteinase inhibitors
Current Oncology Reports, 2004Matrix metalloproteinases (MMPs) are a family of zinc-dependent proteinases that are associated with the tumorigenic process. MMPs degrade the extracellular matrix, promoting tumor invasion and metastasis. They also regulate host defense mechanisms and normal cell function; blocking all MMPs may not lead to a positive therapeutic outcome. Most clinical
Nithya, Ramnath, Patrick J, Creaven
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Matrix metalloproteinases and matrix metalloproteinase inhibitors in lung cancer
Seminars in Oncology, 2002Preclinical studies have provided evidence that matrix metalloproteinases (MMPs), a family of zinc-containing proteolytic enzymes, facilitate tumor invasion, the establishment of metastases, and the promotion of tumor-related angiogenesis. Matrix metalloproteinase inhibitors (MMPIs) have been shown to inhibit tumor growth and dissemination in ...
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The biofilm matrix: multitasking in a shared space
Nature Reviews Microbiology, 2022Hans-Curt Flemming +2 more
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Matrix product states and projected entangled pair states: Concepts, symmetries, theorems
Reviews of Modern Physics, 2021Juan Ignacio Cirac Sasturáin +2 more
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