Results 281 to 290 of about 2,315,187 (340)

Dynamic Immune Cell Composition, Phenotypes, and Signaling in an Engineered Metastatic Niche

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT In breast cancer patients, metastasis is the stage of disease where prognosis significantly worsens. However, the timing at which metastasis initiates and the location of metastatic lesions in an organ are stochastic, limiting the timely identification of disease and the administration of treatments.
Rebecca S. Pereles   +6 more
wiley   +1 more source

Trans-omics landscape of systemic vasculitis identified matrix metalloproteinase 12 as a novel signature molecule. [PDF]

open access: yesRheumatology (Oxford)
Matsumoto K   +17 more
europepmc   +1 more source

Matrix Metalloproteinases

Current Protocols in Cell Biology, 2008
AbstractMatrix metalloproteinases are a class of enzymes that play an important role in the remodeling of the extracellular matrix in development and cancer metastasis. This unit describes a set of methods—cell‐mediated dissolution of type‐1 collagen fibrils, direct and reverse zymography, enzyme capture based on α2‐macroglobulin and TIMP‐1 and ‐2, and
Henning, Birkedal-Hansen   +6 more
  +5 more sources

Labelling Matrix Metalloproteinases

Current Medicinal Chemistry, 2023
Abstract: Matrix metalloproteinases (MMPs) are a family of zinc-containing proteases that participate in many physiological and pathological processes in vivo. Recently, the MMP network has been established according to a deeper understanding of its functions. Some MMPs have been also regarded as biomarkers of various diseases, including inflammation,
Run-Fu Zhang   +3 more
openaire   +2 more sources

Matrix Metalloproteinases

Current Protocols in Cell Biology, 2003
AbstractMatrix metalloproteinases are a class of enzymes that play an important role in the remodeling of the extracellular matrix in development and cancer metastasis. This unit describes a set of methods‐cell‐mediated dissolution of type I collagen fibrils, direct and reverse zymography, enzyme capture based on a‐2 macroglubulin and TIMP‐1 and ‐2 ...
Henning, Birkedal-Hansen   +6 more
openaire   +2 more sources

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