Results 41 to 50 of about 2,335,867 (359)
Frontiers in Pediatrics, 2021 Background: Primary spontaneous pneumothorax is potentially life-threatening, and its recurrence is always a serious problem. Pathological examination provides molecular insights into the pathophysiology of primary spontaneous pneumothorax.Objectives: To
Chih-Yung Chiu +5 more
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Effect of beta-Dystroglycan Processing on Utrophin / DP116 Anchorage in Normal and MDX Mouse Schwann Cell Membrane [PDF]
Neuroscience 141 (18/04/2006) 607-620, 2007 In the peripheral nervous system, utrophin and the short dystrophin isoform (Dp116) are co-localized at the outermost layer of the myelin sheath of nerve fibers; together with the dystroglycan complex. In peripheral nerve, matrix metalloproteinase (MMP) creates a 30 kDa fragment of beta-dystroglycan, leading to a disruption of the link between the ...
arxiv +1 more source
Matrix metalloproteinases and epileptogenesis [PDF]
Molecular and Cellular Pediatrics, 2014 Matrix metalloproteinases are vital drivers of synaptic remodeling in health and disease. It is suggested that at early stages of epileptogenesis, inhibition of matrix metalloproteinases may help ameliorate cell death, aberrant network rewiring, and neuroinflammation and prevent development of epilepsy.
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Liposomic lubricants suppress shear-stress induced inflammatory gene regulation in the joint in vivo [PDF]
arXiv, 2023 Osteoarthritis (OA) is a widespread, debilitating joint disease associated with articular cartilage degradation. It is driven via mechano-inflammatory catabolic pathways, presumed up-regulated due to increased shear stress on the cartilage-embedded chondrocytes, that lead to tissue degeneration.
arxiv
Journal of Ophthalmology, 2022 Purpose. To assess the role of selected matrix metalloproteinases in defective corneal re-epithelization in patients with recurrent corneal erosions. Subjects.
Katarzyna Jadczyk-Sorek +4 more
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Clinics, 2016 OBJECTIVES: This study investigated whether the serum matrix metalloproteinase-9 level is an independent predictor of recurrence after catheter ablation for persistent atrial fibrillation. METHODS: Fifty-eight consecutive patients with persistent atrial
Gang Wu +11 more
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Matrix Metalloproteinases: A Review [PDF]
Critical Reviews in Oral Biology & Medicine, 1993 Matrix metalloproteinases (MMPs) are a family of nine or more highly homologous Zn++endopeptidases that collectively cleave most if not all of the constituents of the extracellular matrix. The present review discusses in detail the primary structures and the overlapping yet distinct substrate specificities of MMPs as well as the mode of activation of ...
Henning Birkedal-Hansen +6 more
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Gelatinases A and B activities in the serum of patients with various coronary artery disease stages [PDF]
Vojnosanitetski Pregled, 2010 Background/Aim. The main characteristic of matrix metalloproteinases (MMPs) is the degradation of extracellular matrix. Synthesis of MMPs has been reported in coronary atherosclerotic lesions in patients with coronary disease (CD) suggesting a pathogenic
Radenković Sandra +3 more
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Journal of Advanced Biotechnology and Experimental Therapeutics, 2023 SARS-CoV-2 stands for severe acute respiratory syndrome coronavirus 2 which is the causative agent of spreading coronavirus disease 2019 that is known as COVID-19 pandemic, the disease leads to severe acute respiratory illness. Matrix metalloproteinases-
May K. Ismael +2 more
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Injectable and bioresponsive hydrogels for on-demand matrix metalloproteinase inhibition
Nature Materials, 2014 Inhibitors of matrix metalloproteinases (MMPs) have been extensively explored to treat pathologies where excessive MMP activity contributes to adverse tissue remodeling.
B. Purcell +14 more
semanticscholar +1 more source