Results 51 to 60 of about 2,315,187 (340)
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Pakistan Journal of Medicine and DentistryBackground: Fibrotic lung diseases were seen to have devastating effects among patients globally. Matrix metalloproteinases (MMP) including MMP-7, MMP-9, and MMP-1 have become promising biomarkers for idiopathic pulmonary fibrosis (IPF), and other ...
Mehvish Aqil +6 more
doaj +1 more source
Matrix Metalloproteinase-1 and Matrix Metalloproteinase-9 in the Aqueous Humor of Diabetic Macular Edema Patients. [PDF]
PLoS ONE, 2016 To assess the concentrations of matrix metalloproteinase (MMP)-1 and MMP-9 in the aqueous humor of diabetic macular edema (DME) patients.The concentrations of MMP-1 and MMP-9 in the aqueous humors of 15 cataract patients and 25 DME patients were compared.
Jin-Woo Kwon, Jin A Choi, Donghyun Jee
doaj +1 more source
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
Aging and Cancer, EarlyView.As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
Matrix Metalloproteinases [PDF]
Journal of Biological Chemistry, 1999 H, Nagase, J F, Woessner
+6 more sources
Patologìâ, 2014 Aims. In order to study the levels of matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1, intracardiac hemodynamics, frequency of acute cardiac aneurysm development in patients with Q-wave myocardial infarction after thrombolysis, 74 ...
V. D. Syvolap , S. M. Kyselov
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic +6 more
wiley +1 more source
Neurology India, 2011 Matrix metalloproteinases (MMPs) are a major group of enzymes that regulate cell–matrix composition. The MMPs are zinc-dependent endopeptidases known for their ability to cleave one or several (extracellular matrix) ECM constituents, as well as nonmatrix proteins.
Evrosimovska, Biljana +3 more
openaire +3 more sources
Matrix metalloproteinase 7 in diagnosis and differentiation of pulmonary arterial hypertension
Pulmonary Circulation, 2019 Pulmonary arterial hypertension is a severe disease for which diagnosis often is delayed. Matrix metalloproteinases have been suggested to play a role in vascular remodeling and pulmonary hypertension development. Our aim was therefore to investigate the
Mattias Arvidsson +3 more
doaj +1 more source
Arthritis Care &Research, Accepted Article.Objective A leading cause of death among scleroderma (SSc) patients, interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M Padilla +13 more
wiley +1 more source