Results 1 to 10 of about 122,315 (249)

Detecting the PEX Like Domain of Matrix Metalloproteinase-14 (MMP-14) with Therapeutic Conjugated CNTs [PDF]

Biosensors, 2022
Matrix metalloproteinases (MMPs) are essential proteins acting directly in the breakdown of the extra cellular matrix and so in cancer invasion and metastasis.
D. Vieira, J. Barralet, E. J. Harvey, G. Merle   +3 more
doaj   +4 more sources

Matrix metalloproteinase 14 is required for fibrous tissue expansion [PDF]

eLife, 2015
Type I collagen-containing fibrils are major structural components of the extracellular matrix of vertebrate tissues, especially tendon, but how they are formed is not fully understood.
Susan H Taylor, Ching-Yan Chloé Yeung, Nicholas S Kalson, Yinhui Lu, Paola Zigrino, Tobias Starborg, Stacey Warwood, David F Holmes, Elizabeth G Canty-Laird, Cornelia Mauch, Karl E Kadler   +10 more
doaj   +4 more sources

Matrix metalloproteinase‐14 (MMP‐14) downregulation inhibits esophageal squamous cell carcinoma cell migration, invasion, and proliferation [PDF]

Thoracic Cancer, 2020
Background Matrix metalloproteinase‐14 (MMP‐14) is known to be a key regulator of oncogenesis and tumor progression. The present study was designed to assess the relationship between the downregulation of MMP‐14 and the in vitro proliferative, migratory,
Nanzheng Chen, Guangjian Zhang, Junke Fu, Qifei Wu   +3 more
doaj   +5 more sources

Matrix metalloproteinase 14 in the zebrafish: an eye on retinal and retinotectal development. [PDF]

PLoS ONE, 2013
Matrix metalloproteinases (MMPs) are members of the metzincin superfamily of proteinases that cleave structural elements of the extracellular matrix and many molecules involved in signal transduction.
Els Janssens, Djoere Gaublomme, Lies De Groef, Veerle M Darras, Lut Arckens, Nathalie Delorme, Filip Claes, Inge Van Hove, Lieve Moons   +8 more
doaj   +4 more sources

RETRACTED: ACADL Functions as a Tumor Suppressor in Hepatocellular Carcinoma Metastasis by Inhibiting Matrix Metalloproteinase 14 [PDF]

Frontiers in Oncology, 2022
High aggressiveness is the main reason for the poor prognosis of hepatocellular carcinoma (HCC) patients. However, its molecular mechanisms still remain largely unexplored.
Danfeng Guo, Danfeng Guo, Danfeng Guo, Xiaodan Zhang, Xiaodan Zhang, Xiaodan Zhang, Honglei Cui, Honglei Cui, Honglei Cui, Dongsheng Yu, Dongsheng Yu, Dongsheng Yu, Huapeng Zhang, Huapeng Zhang, Huapeng Zhang, Xiaoyi Shi, Xiaoyi Shi, Xiaoyi Shi, Chun Pang, Chun Pang, Chun Pang, Jie Li, Jie Li, Jie Li, Wenzhi Guo, Wenzhi Guo, Wenzhi Guo, Shuijun Zhang, Shuijun Zhang, Shuijun Zhang   +29 more
doaj   +2 more sources

Tumour Suppressor Neuron Navigator 3 and Matrix Metalloproteinase 14 are Co-expressed in Most Melanomas but Downregulated in Thick Tumours [PDF]

Acta Dermato-Venereologica, 2023
Melanoma is a highly metastatic tumour originating from neural crest-derived melanocytes. The aim of this study was to analyse the expression of neuron navigator 3 (NAV3) in relation to membrane type-1 matrix metalloproteinase MMP14, a major regulator of
Olga Bugaeva, Pilvi Maliniemi, Wenche S. Prestvik, Eeva Leivo, Nicolas Kluger, Alexander Salava, Sanna Virtanen, Kirsi Jäntti, Olli Saksela, Kaisa Lehti, Paula Kujala, Kaj Krohn, Annamari Ranki   +12 more
doaj   +2 more sources

Matrix Metalloproteinase 14 promotes lung cancer by cleavage of Heparin-Binding EGF-like Growth Factor [PDF]

Neoplasia: An International Journal for Oncology Research, 2017
Molecularly targeted therapies benefit approximately 15–20% of non-small cell lung cancer (NSCLC) patients carrying specific drug-sensitive mutations.
Marcin Stawowczyk, Max D. Wellenstein, Sharrell B. Lee, Shira Yomtoubian, Anna Durrans, Hyejin Choi, Navneet Narula, Nasser K. Altorki, Dingcheng Gao, Vivek Mittal   +9 more
doaj   +2 more sources

Retraction: ACADL functions as a tumor suppressor in hepatocellular carcinoma metastasis by inhibiting matrix metalloproteinase 14 [PDF]

Frontiers in Oncology
Frontiers Editorial Office
doaj   +2 more sources

Maternal Serum Matrix Metalloproteinase 14 (MMP14) in Early Onset Preeclampsia and Normal Pregnancy [PDF]

SHS Web of Conferences, 2020
Matrix Metalloproteinases 14 presumably play for cytotrophoblast migration and invasion of the uterine wall and in the remodeling of the spiral arteries in pregnancy.
Sumawan H, Sutrisno
doaj   +1 more source

Leptin and Pro-Inflammatory Stimuli Synergistically Upregulate MMP-1 and MMP-3 Secretion in Human Gingival Fibroblasts. [PDF]

PLoS ONE, 2016
Gingival fibroblast-mediated extracellular matrix remodelling is implicated in the pathogenesis of periodontitis, yet the stimuli that regulate this response are not fully understood.
Rachel C Williams, Andrew J Skelton, Stephen M Todryk, Andrew D Rowan, Philip M Preshaw, John J Taylor   +5 more
doaj   +1 more source