Results 101 to 110 of about 122,315 (249)
High serum MMP-14 predicts worse survival in gastric cancer.
PLoS ONE, 2018 Matrix metalloproteinases (MMPs), endopeptidases with diverse biochemical functions, can promote cancer cell invasion and metastasis by degrading the extracellular matrix.
Aaro Kasurinen +6 more
doaj +1 more source
Matrix metalloproteinase 14 (MMP14) is differentially expressed in breast cancer metastases.
, 2020 Breast cancer is a leading cause of death for women (1, 2). We mined public datasets to understand the most significant transcriptional and epigenomic changes between primary tumors of the breast and the metastases that they generate (3-6). In metastases to both the brain (3) and the bones (4), the matrix metalloproteinase 14 (MMP14) was among the ...
openaire +2 more sources
Isolation Defines Identity: Functional Consequences of Extracellular Vesicle Purification Strategies
Advanced Healthcare Materials, EarlyView.Four extracellular vesicle purification strategies are compared using ovarian‐cancer ascites and ES‐2 cell supernatants. A novel workflow links purification to function by combining particle‐normalized proteomics with matched cell‐free and cell‐based assays.
Christian Preußer +10 more
wiley +1 more source
Secreted matrix metalloproteinase-14 is a predictor for antifibrotic effect of IC-2-engineered mesenchymal stem cell sheets on liver fibrosis in mice. [PDF]
Regen Ther, 2021 Fukushima K +11 more
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum +5 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This study exploits the plasticity of ASCs‐derived cartilage organoids which generate a perichondrial layer of MSCs when exposed to cyclic chondrogenic/proliferative cues. Using these organoids as building blocks, we develop (i) Phalange Shaped Tissue Engineered Cartilage (Pa‐TECs), recapitulating endochondral ossification suitable for the treatment of
Pablo Pfister +14 more
wiley +1 more source
Oral Mucosal Responses to Titanium and Composite Resin: An Immunohistochemical Study
Al-Rafidain Dental JournalAims: The current study aimed to evaluate the healing process of the oral mucosa over a submucosal contact with Titanium and Composite resin. Materials and Methods: 24 male New Zealand rabbits were subjected to this study.
Ahmed Farooq Khaleel +2 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.This study evaluates 3D‐printed recombinant spider silk hydrogel eADF4(C16)‐RGD in a rat AV loop model for tissue engineering. Constructs with T17b endothelial progenitor cells showed enhanced vascularization and biodegradation. Results highlight the importance of scaffold design and cellular integration in improving vascular density and overall ...
Claire M. Weinhold +9 more
wiley +1 more source
Biochemistry Research International, 2012 Spatial and temporal regulation of the pericellular proteolytic environment by local growth factors, such as EGF and TGF-β, initiates a wide repertoire of cellular responses coupled to a plasmin/matrix metalloproteinase (MMP) dependent stromal-remodeling
Cynthia E. Wilkins-Port +4 more
doaj +1 more source
An In Situ Embedded B‐MOF Sponge With Shape‐Memory for All‐in‐One Diabetic Wound Therapy
Advanced Healthcare Materials, EarlyView.A smart shape‐memory sponge dressing (P1A3@B‐MOF) is developed for accelerated diabetic wound healing. It achieves pH‐responsive corelease of Zn2+ and salvianolic acid B, synergistically providing antibacterial action, repolarizing macrophages to the M2 phenotype, and promoting angiogenesis.
Hai Zhou +11 more
wiley +1 more source