Results 41 to 50 of about 122,315 (249)

Effects of Qualea grandiflora Extract on the Expression of MMP-14 and HIF-1α in Cultured Fibroblasts and Preosteoblasts

open access: yesBrazilian Archives of Biology and Technology, 2021
Background: Qualea grandiflora (QG) (Vochysiaceae), also known as "pau-ferro", "pau-terra" or "pau-de-tucano", is a very common deciduous tree in the Brazilian Cerrado used in traditional medicine to treat inflammations, ulcers, diarrhea, and infections.
Gabriela Silva Neubern de Oliveira   +7 more
doaj   +1 more source

MATRIX METALLOPROTEINASE -14 AND MATRIX METALLOPROTEINASE -13 ARE THE POTENTIAL MARKERS OF THE CHRONIC PERIODONTITIS

open access: yesBiological Markers in Fundamental and Clinical Medicine (collection of abstracts), 2018
MATRIX METALLOPROTEINASE -14 AND MATRIX METALLOPROTEINASE -13 ARE THE POTENTIAL MARKERS OF THE CHRONIC ...
E.L. Kolb, L.A. Kazeko
openaire   +2 more sources

Competitive disruption of the tumor-promoting function of membrane type 1 matrix metalloproteinase/matrix metalloproteinase-14 in vivo

open access: yesMolecular Cancer Therapeutics, 2005
Abstract Membrane type 1 matrix metalloproteinase (MT1-MMP) is a potent modulator of the pericellular environment and promotes tumor cell invasion and proliferation in many types of tumor. The activation of proMMP-2 and processing of collagen I by MT1-MMP have been thought to be important for its tumor-promoting function.
Nonaka, T   +4 more
openaire   +2 more sources

A novel gene mutation for multicentric osteolysis nodulosis and arthropathy: Case report and review of literature

open access: yesHeliyon, 2023
Frank-Ter Haar syndrome (FTHS), Winchester syndrome (WS), Torg syndrome (TS) and Multicentric Osteolysis Nodulosis and Arthropathy (MONA) are progressive skeletal dysplasia consisting of acro-osteolysis.
Marjan Shakiba, Fariba Alaei
doaj   +1 more source

Development of Radiolabeled Membrane Type-1 Matrix Metalloproteinase Activatable Cell Penetrating Peptide Imaging Probes

open access: yesMolecules, 2015
Membrane type-1 matrix metalloproteinase (MT1-MMP or MMP-14) plays an important role in adverse cardiac remodelling. Here, we aimed to develop radiolabeled activatable cell penetrating peptides (ACPP) sensitive to MT1-MMP for the detection of elevated ...
Sander M. J. van Duijnhoven   +3 more
doaj   +1 more source

The role of matrix metalloproteinase in the intimal sarcoma-like cells derived from endarterectomized tissues from a chronic thromboembolic pulmonary hypertension patient. [PDF]

open access: yesPLoS ONE, 2014
Sarcoma-like cells (SCLs) were derived from endarterectomized tissue of a single chronic thromboembolic pulmonary hypertension (CTEPH) patient during incubation of those thrombi at second passage as described at our previous report.
Takayuki Jujo   +7 more
doaj   +1 more source

Mechanism of matrix metalloproteinase-14 (mmp-14) regulation during atherosclerosis [PDF]

open access: yes, 2018
"December 2006" ; The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. ; Vita. ; Thesis (Ph.
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Small leucine-rich proteoglycans and matrix metalloproteinase-14: Key partners?

open access: yesMatrix Biology, 2019
Small leucine-rich proteoglycans (SLRPs) are important regulators of extracellular matrix assembly and cell signaling. They are a family of proteoglycans that are present in extracellular matrix and that share in common multiple repeats of a leucine-rich structural motif. SLRPs have been identified as inhibitors of cancer progression by affecting MMPs,
Katarzyna Pietraszek-Gremplewicz   +7 more
openaire   +3 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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