Results 211 to 220 of about 700,477 (342)

Matrix metalloproteinase 2 (MMP2); MMP9 [PDF]

Science-Business eXchange, 2012
openaire   +1 more source

SIRT1 enhances matrix metalloproteinase‐2 expression and tumor cell invasion in prostate cancer cells

The Prostate, 2013
J. Lovaas, Lijia Zhu, Christine Y. Chiao, Vanessa Byles, D. Faller, Yan Dai   +5 more
semanticscholar   +1 more source

Modulating Integrin and Growth Factor Signaling With Peptides: Strategies to Synergistically Enhance Bone Tissue Regeneration

Advanced Science, EarlyView.
It has been demonstrated that, in the bone extracellular matrix (ECM), integrins and growth factor receptors (GFRs) engage in synergistic signaling to guide bone healing and regeneration. This review provides a comprehensive overview of current strategies using ECM‐derived peptides to recreate the cellular microenvironment and harness synergistic ...
Lluís Oliver‐Cervelló, Elisabetta Ada Cavalcanti‐Adam, Carlos Mas‐Moruno   +2 more
wiley   +1 more source

Matrix metalloproteinase-2 and pH-responsive drug eluting multilayer as intraocular lens coating to improve the posterior capsule opacification inhibition. [PDF]

Regen Biomater
Han Y, Wang J, Chen H, Lin Q.
europepmc   +1 more source

Vitamin A, D, E, and K as Matrix Metalloproteinase-2/9 Regulators That Affect Expression and Enzymatic Activity. [PDF]

Int J Mol Sci, 2023
Vo HVT, Nguyen YT, Kim N, Lee HJ.
europepmc   +1 more source

Fibroblast Activation Protein Promotes Thoracic Aortic Dissection via PLAUR/ITGB1‐Mediated Pro‐inflammatory Macrophage Polarization

Advanced Science, EarlyView.
This study reveals that FAP promotes thoracic aortic dissection (TAD) through a nonenzymatic mechanism involving fibroblast‐macrophage crosstalk via the FAP/PLAUR/ITGB1/FAK axis. Targeting this pathway might offer a promising therapeutic strategy for TAD.
Hongqiao Zhu, Jianlie Wu, Ziyi Xu, Yifei Pei, Zaiping Jing, Jian Zhou, Rui Feng, Junjun Liu   +7 more
wiley   +1 more source

High matrix metalloproteinase-2 expression predicts poor prognosis of colon adenocarcinoma and is associated with PD-L1 expression and lymphocyte infiltration. [PDF]

PeerJ
Xiao Y, Li G, Xie Y, Shao B, Hao J, Zhu Y, Kong D, Qin Y, Qin H, Ren S, Wang H, Sun C, Wang H.   +12 more
europepmc   +1 more source

Protease‐Activated Plasmonic Nanosensors for Predictive Ultrasound‐Guided Photoacoustic Imaging of Tumor Responses to Adoptive T Cell Therapy

Advanced Science, EarlyView.
Protease‐activated plasmonic nanosensors are demonstrated to noninvasively monitor antitumor T cell activity in tumors with anatomical information upon adoptive T cell transfer via ultrasound‐guided photoacoustic imaging. These nanosensors are actuated by granzyme B, a protease secreted by activated cytotoxic T cells during tumor cell killing, which ...
Myeongsoo Kim, Seoyoon Song, Ali Zamat, Paul S. Pelkowski, Shivashankar Subramanian, Melissa Cadena, Sydney Fabrega, Meredith Brienen, Jinhwan Kim, Gabriel A. Kwong, Stanislav Y. Emelianov   +10 more
wiley   +1 more source

The rs243865 Polymorphism in Matrix Metalloproteinase-2 and its Association With Target Organ Damage in Patients With Resistant Hypertension: Cross-Sectional Study. [PDF]

JMIR Cardio
Tuan Huynh A, Vu HA, Chuong HQ, Anh TH, Viet Tran A.   +4 more
europepmc   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source