Results 71 to 80 of about 244,599 (206)

Purification of a fragment obtained by autolysis of a PIIIb-SVMP from Bothrops alternatus venom [PDF]

, 2018
Snake Venom Metalloproteinases (SVMPs) represent 43.1% of the components in Bothrops alternatus venom and play an important role in envenomation. Disintegrins and disintegrin-like domains are released by proteolytic processing of PII and PIII classes of ...
Acosta, Ofelia Cristina, Biscoglio, Mirtha Josefa, Bustillo, Soledad, dos Santos, Patty Karina, Gay, Claudia Carolina, Leiva, Laura Cristina Ana, Olivera Moritz, Milene Nobrega de, Rodríguez, Juan Pablo, Sobreiro Selistre de Araujo, Heloisa, Van de Velde, Andrea Carolina   +9 more
core   +1 more source

Matrix metalloproteinases in human gliomas: activation of matrix metalloproteinase-2 (MMP-2) may be correlated with membrane-type-1 matrix metalloproteinase (MT1-MMP) expression [PDF]

Journal of Korean Medical Science, 2000
To evaluate possible roles of matrix metalloproteinase (MMP)-1, -2, tissue inhibitor of metalloproteinase (TIMP)-1, -2 and membrane-type-1 matrix metalloproteinase (MT1-MMP) in invasion of human gliomas, expressions of these proteins were investigated in ten cases of human glioma and two meningioma tissues and eight human glioma cell lines.
J H, Hur, M J, Park, I C, Park, D H, Yi, C H, Rhee, S I, Hong, S H, Lee   +6 more
openaire   +2 more sources

Matrix metalloproteinase-2, tissue inhibitor of matrix metalloproteinase-2, and transforming growth factor beta 1 in the aqueous humor and serum of patients with pseudoexfoliation syndrome

Clinical Ophthalmology, 2014
Selcuk Kara,1 Nilgun Yildirim,2 Ahmet Ozer,2 Omer Colak,3 Afsun Sahin21Department of Ophthalmology, Canakkale Onsekiz Mart University School of Medicine, Canakkale, 2Department of Ophthalmology, Eskisehir Osmangazi University Hospitals, Meselik ...
Kara S, Yildirim N, Ozer A, Colak O, Sahin A   +4 more
doaj  

Development of Matrix Metalloproteinase-2 Inhibitors for Cardioprotection

Frontiers in Pharmacology, 2018
The objective of our present study is to develop novel inhibitors for MMP-2 for acute cardioprotection. In a series of pilot studies, novel substituted carboxylic acid derivatives were synthesized based on imidazole and thiazole scaffolds and then tested
Péter Bencsik, Péter Bencsik, Krisztina Kupai, Anikó Görbe, Anikó Görbe, Éva Kenyeres, Éva Kenyeres, Zoltán V. Varga, János Pálóczi, Renáta Gáspár, László Kovács, Lutz Weber, Ferenc Takács, István Hajdú, István Hajdú, Gabriella Fabó, Sándor Cseh, László Barna, László Barna, Tamás Csont, Csaba Csonka, György Dormán, Péter Ferdinandy, Péter Ferdinandy   +23 more
doaj   +1 more source

Hyperhomocysteinemia induced by excessive methionine intake promotes rupture of cerebral aneurysms in ovariectomized rats. [PDF]

, 2016
BackgroundHyperhomocysteinemia (HHcy) is associated with inflammation and a rise in the expression of matrix metalloproteinase-9 (MMP-9) in the vascular wall.
Hashimoto, Tomoki, Kanematsu, Yasuhisa, Kitazato, Keiko T, Korai, Masaaki, Matsushita, Nobuhisa, Miyamoto, Takeshi, Nagahiro, Shinji, Satomi, Junichiro, Shimada, Kenji, Tada, Yoshiteru   +9 more
core   +2 more sources

Immunocharacterization of matrix metalloproteinase-2 and matrix metalloproteinase-9 in canine transmissible venereal tumors

Biotechnic & Histochemistry, 2017
Matrix metalloproteases (MMPs) are endogenous proteases that are responsible for degradation of extracellular matrix (ECM) proteins and cell surface antigens. The breakdown of ECM participates in the local invasion and distant metastases of malignant tumors.
A Akkoc, D Nak, A Demirer, G Şimşek
openaire   +4 more sources

Expression of MMP-2, MMP-9 and TIMP-2 in pituitary tumors and their relationship with cavernous sinus invasion

Endocrine Oncology
Objective: To evaluate the expression of matrix metalloproteinase-2 (MMP-2), MMP-9 and tissue inhibitor of metalloproteinase-2 (TIMP-2) in pituitary tumors and investigate their correlation with circulating plasma proteins and cavernous sinus invasion ...
Ane Caroline Thé B Freire, Raquel S Jallad, Rafael L Batista, Andrea Glezer, Marcio C Machado, Gilberto Ochman, Valter A Cescato, Malebranche Berardo Carneiro Cunha Neto, Fernando P Frassetto, Raphael S S de Medeiros, Ericka B Trarbach   +10 more
doaj   +1 more source

LTD4 and TGF-β1 induce the expression of metalloproteinase-1 in chronic rhinosinusitis via a cysteinyl leukotriene receptor 1-related mechanism [PDF]

, 2016
A
Bachert, Claus, Claeys, Cindy, Holtappels, Gabriële, Perez Novo, Claudina, Pezato, Rogerio   +4 more
core   +2 more sources

Matrix Metalloproteinase 2 Activation in Cultured Corneas

Ophthalmic Research, 2000
<i>Purpose:</i> Corneas that are maintained in tissue culture medium shed their epithelial cells and repopulation following graft surgery is an essential facet of the healing process. Failure to do so may be a result of structural damage to the epithelial basement membrane of a donor cornea.
V A, Smith, A, El-Rakhawy, D L, Easty
openaire   +2 more sources

Clinical significance of matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1 and 2 in Kawasaki disease [PDF]

Korean Journal of Pediatrics, 2010
Purpose : Kawasaki disease (KD) is a systemic vasculitis, a leading cause of pediatric acquired heart disease. Histopathological findings of coronary artery lesion (CAL) in KD indicate destruction of the coronary artery wall with diffuse vasculitis ...
Ki Wook Yun, Sin Weon Sin, Jung Ju Lee, Soo Ahn Chae, In Seok Lim, Eung Sang Choi, Byoung Hoon Yoo, Mi-Kyung Lee   +7 more
doaj   +1 more source