Inhibition of interleukin-1β-stimulated collagenase and stromelysin expression in human tendon fibroblasts by epigallocatechin gallate ester [PDF]
The medicinal benefits of green tea (Camellia sinensis) consumption have been attributed to bioavailable polyphenols, notably epigallocatechin gallate (EGCG).
Buttle, David J. +4 more
core +1 more source
Possible Mechanism of Betel-quid-extract-induced Expression of Matrix Metalloproteinase-2
Betel quid extract (BQE) has been demonstrated to induce matrix metalloproteinase (MMP)-2 expression. This study aimed to establish the possible mechanism involved in this event. Methods: Western blotting, reverse-transcription polymerase chain reaction,
Yu-Chi Liu +10 more
doaj +1 more source
Evaluation of MMP‑2, MMP‑9, TIMP‑1, TIMP‑2, NGAL and MMP‑9/NGAL complex in urine and sera from patients with bladder cancer [PDF]
The identification of biomarkers in urine or serum samples from patients with bladder cancer is urgently required for the development of non-invasive methods for the diagnosis of bladder carcinoma and to facilitate follow-up surveillance, to combat the ...
Bruzzese, Dario +2 more
core +1 more source
The potential for dietary factors to prevent or treat osteoarthritis [PDF]
Osteoarthritis (OA) is a degenerative joint disease for which there are no disease-modifying drugs. It is a leading cause of disability in the UK. Increasing age and obesity are both major risk factors for OA and the health and economic burden of this ...
Bao, Yongping +8 more
core +1 more source
PECULIARITIES OF THE FIBROSIS AND CIRRHOSIS MONITORING AMONG CHILDREN WITH CHRONIC LIVER DISEASES
The researchers examined the opportunities to use determination in the serum among children with chronic liver diseases of various etiologies of the hyaluronic acid levels, collagen type IV, matrix metalloproteinase-2, tissue inhibitor of the matrix ...
A.N. Surkov +4 more
doaj +2 more sources
Matrix Metalloproteinase-9 and Inflammation in Different Types of Multiple Sclerosis [PDF]
Different clinical courses of multiple sclerosis, heterogeneity of its clinical implications, different effect of immunomodulatory therapy for the same clinical forms implies various pathogenetic mechanisms of central nervous system damage at this ...
Chernenko, M. (Maksym) +4 more
core +2 more sources
Background: Matrix metalloproteinases-2 and -9 play important roles in the development of breast cancer by hydrolyzing the extracellular matrix. Since −1306C/T and −1562C/T polymorphisms are located at the promoter regions of the matrix metalloproteinase-
Zahra Dehghan Manshadi +4 more
doaj
Insights into the structure and dynamics of lysyl oxidase propeptide, a flexible protein with numerous partners [PDF]
Lysyl oxidase (LOX) catalyzes the oxidative deamination of lysine and hydroxylysine residues in collagens and elastin, which is the first step of the cross-linking of these extracellular matrix proteins.
Duclos, Bertrand +6 more
core +3 more sources
Wen-jing Zhang, Bing Song, Tao Yang Department of General Surgery, Tianjin First Central Hospital, Tianjin 300192, People’s Republic of ChinaCorrespondence: Bing Song Email song2002bing@163.comIntroduction: The objective of this study was to assess
Zhang W, Song B, Yang T
doaj
Divergent functions for airway epithelial matrix metalloproteinase 7 and retinoic acid in experimental asthma. [PDF]
The innate immune response of airway epithelial cells to airborne allergens initiates the development of T cell responses that are central to allergic inflammation.
Angkasekwinai, Pornpimon +14 more
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