Results 121 to 130 of about 331,204 (356)
Targeting matrix metalloproteinase MMP3 greatly enhances oncolytic virus mediated tumor therapy
Translational Oncology, 2021 In cancer, the extracellular matrix is extensively remodeled during chronic inflammation, thus affecting cell transcription, differentiation, migration and cell-cell interactions.
Minglong Liang +8 more
doaj
A multiscale mathematical model of tumour invasive growth [PDF]
arXiv, 2016 Known as one of the hallmarks of cancer [30], cancer cell invasion of human body tissue is a complicated spatio-temporal multiscale process which enables a localised solid tumour to transform into a systemic, metastatic and fatal disease. This process explores and takes advantage of the reciprocal relation that solid tumours establish with the ...
arxiv
Correlation of Matrix Metalloproteinases and Tissue Inhibitors of Matrix Metalloproteinase Expression in Ileal Carcinoids, Lymph Nodes and Liver Metastasis with Prognosis and Survival [PDF]
, 2009 Purpose: Ileal carcinoids are gut epithelial tumors originating from serotonin-containing enterochromaffin (EC) cells. Therapeutic options for effectively inhibiting the growth and spread of metastatic carcinoids are still limited.
Baur, Dorothee M. +8 more
core +2 more sources
Unperceivable Designs of Wearable Electronics
Advanced Materials, EarlyView.Unperceivable wearable technologies seamlessly integrate into everyone's daily life, for healthcare and Internet‐of‐Things applications. By remaining completely unnoticed both visually and tactilely, by the user and others, they ensure medical privacy and allow natural social interactions.
Yijun Liu +2 more
wiley +1 more source
The Structural Biology and Critical Evaluation of Bacterial Proteases as Targets in New Drug Design [PDF]
arXiv, 2014 Bacteria produce a range of proteolytic enzymes, for which a number human equivalent or structurally similar examples exist and the primary focus of this study was to analyse the published literature to find proteolytic enzymes, specifically endoproteses and to examine the similarity in the substrates that they act on so as to predict a suitable ...
arxiv
Membrane type-matrix metalloproteinases and tumor progression [PDF]
, 2005 Matrix metalloproteinases (MMPs) are a family of zinc endopeptidases that process growth factors, growth factor binding proteins, cell surface proteins, degrade extracellular matrix (ECM) components and thereby play a central role in tissue remodeling ...
Noël, Agnès, Sounni, Nor Eddine
core +1 more source
Spatially Controlled 3‐D Multiplexed Aptamer Patterning in Hydrogels
Advanced Materials Interfaces, EarlyView.A hydrogel platform based on norbornene‐functionalized polyvinyl alcohol enables high‐resolution, 3‐D multiplexed patterning of DNA aptamers via two‐photon polymerization. Two distinct aptamers are covalently immobilized with single micron‐scale precision across the x, y, and z dimensions.
Kevin Roost +9 more
wiley +1 more source
Kidney Fibrosis and Matrix Metalloproteinases (MMPs)
Frontiers in Bioscience-LandmarkChronic kidney disease (CKD) is a disorder that causes changes in both the structure and function of the kidneys, causing complications such as hypertension, edema, and oliguria. Renal fibrosis is also a common pathological feature of CKD.
Antonella La Russa +11 more
doaj +1 more source
Clinics, 2018 Infection with human papillomaviruses is associated with a series of benign and malignant hyperproliferative diseases that impose a heavy burden on human populations.
Suellen Herbster +3 more
doaj +1 more source
Tuning the Morphological Properties of Granular Hydrogels to Control Lymphatic Capillary Formation
Advanced Materials Interfaces, EarlyView.Tuning the morphological properties of granular hydrogels is essential to generate robust lymphatic capillary networks that express key lymphatic gene and protein markers. The study demonstrates that 3D in vitro lymphatic tube formation is controlled not by the mechanical properties of the gel, but by the pore size and topology (periodicity) of the gel
Daniel Montes +7 more
wiley +1 more source