Results 131 to 140 of about 331,204 (356)

ROCK signaling promotes collagen remodeling to facilitate invasive pancreatic ductal adenocarcinoma tumor cell growth [PDF]

open access: yes, 2017
Pancreatic ductal adenocarcinoma (PDAC) is a major cause of cancer death; identifying PDAC enablers may reveal potential therapeutic targets. Expression of the actomyosin regulatory ROCK1 and ROCK2 kinases increased with tumor progression in human and ...
Anderson, Kurt I.   +12 more
core   +1 more source

Progress in Surface Plasmon and Other Resonance Biosensors for Biomedical Applications

open access: yesAdvanced Materials Technologies, EarlyView.
This is the shortened version: Recent advancements in surface plasmon resonance and other optical resonance biosensors for biomedical applications are presented. Advanced sensing strategies are examined for the detection of diverse analytes, integration of nanomaterials and machine learning, and emerging nonplasmonic modes like guided mode resonance ...
Faten Bashar Kamal Eddin   +8 more
wiley   +1 more source

A hydroxamic acid-methacrylated collagen conjugate for the modulation of inflammation-related MMP upregulation [PDF]

open access: yesJournal of Materials Chemistry B 2018, 2018
Medical devices with matrix metalloproteinase (MMP) modulating functionality are highly desirable to restore tissue homeostasis in critical inflammation states, such as chronic wounds, rotator cuff tears and cancer. The introduction of MMP-modulating functionality in such devices is typically achieved via loading of either rapidly-diffusing chelating ...
arxiv  

The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) family [PDF]

open access: yes, 2015
The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) enzymes are secreted, multi-domain matrix-associated zinc metalloendopeptidases that have diverse roles in tissue morphogenesis and patho-physiological remodeling, in ...
A Colige   +145 more
core   +1 more source

Modern Strategies in Wound Healing: The Rise of Bacterial Cellulose Dressings

open access: yesAdvanced Therapeutics, EarlyView.
Bacterial cellulose (BC)‐based wound dressings combine high water retention, biocompatibility, and mechanical strength to support wound healing. This review highlights advanced functionalization strategies and fabrication techniques that enhance BC's therapeutic performance, establishing it as a promising material for next‐generation wound care ...
Elif Naz Gürsoy   +4 more
wiley   +1 more source

Effects of Diet-Induced Obesity on Extracellular Matrix Remodeling During Skeletal Muscle Regeneration [PDF]

open access: yes, 2016
THE EFFECT OF DIET-INDUCED OBESITY ON EXTRACELLULAR MATRIX REMODELING DURING SKELETAL MUSCLE REGENERATION Michelle A. Tedrowe, Lemuel A. Brown, Richard A. Perry Jr., Megan E. Rosa, Jacob L. Brown, David E. Lee, Nicholas P. Greene, Tyrone A.
Tedrowe, Michelle A
core   +2 more sources

Advances in Microfluidic Cochlea‐On‐A‐Chip

open access: yesAdvanced Science, EarlyView.
This review systematically examines diverse cell sources for inner ear organoids and outlines stepwise induction protocols. Furthermore, it discusses current applications and prospective developments of cochlea‐on‐a‐chip technologies in areas such as deafness modeling, mechanistic studies, and drug evaluation, with particular focus on gene‐therapy drug
Tian Shen   +10 more
wiley   +1 more source

Matrix metalloproteinases in exercise and obesity

open access: yesVascular Health and Risk Management, 2016
Jonathan Jaoude,1 Yunsuk Koh2 1Department of Biology, 2Department of Health, Human Performance, and Recreation, Baylor University, Waco, TX, USA Abstract: Matrix metalloproteinases (MMPs) are zinc- and calcium-dependent endoproteinases that have the ...
Jaoude J, Koh Y
doaj  

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