Results 181 to 190 of about 331,204 (356)

The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family.

, 1990
Harold E. Van Wart, Henning Birkedal‐Hansen   +1 more
openalex   +1 more source

Gelatinase-A (MMP-2), gelatinase-B (MMP-9) and membrane type matrix metalloproteinase-1 (MT1-MMP) are involved in different aspects of the pathophysiology of malignant gliomas [PDF]

, 1999
Peter Forsyth, H Wong, T D Laing, N. B. Rewcastle, D G Morris, Huong Muzik, K J Leco, R.N. Johnston, P M A Brasher, G Sutherland, Dylan R. Edwards   +10 more
openalex   +1 more source

Responsive ROS‐Augmented Prodrug Hybridization Nanoassemblies for Multidimensionally Synergitic Treatment of Hepatocellular Carcinoma in Cascade Assaults

Advanced Science, EarlyView.
This study proposes a novel HCC therapy using CA‐4S2@ES‐Cu nanomedicines to amplify cuproptosis, enhancing chemotherapy and immunotherapy. CA‐4 and ES‐Cu synergistically inhibit tumor growth, induce immune responses, and reverse the immunosuppressive microenvironment, offering an effective multidimensional therapeutic strategy for HCC treatment ...
Yingjie Zeng, Yuening Cao, Senmiao Ren, Chaozheng Zhang, Jianan Liu, Ke Liu, Yan Wang, Hongyu Chen, Fengjiao Zhou, Xiuli Yang, Xian Ge, Tingting Zhang, Tianbao Wang, Yao He, Defang Li, Chuantao Zhang, Jun Lu   +16 more
wiley   +1 more source

Human neutrophil collagenase. A distinct gene product with homology to other matrix metalloproteinases.

, 1990
Karen A. Hasty, Tayebeh Pourmotabbed, Gregory I. Goldberg, James P. Thompson, Dominic G. Spinella, Rowena Stevens, Carlo L. Mainardi   +6 more
openalex   +1 more source

Inhibition and Rescue of Hyperglycemia‐Induced Cellular Senescence by Mitochondrial Transfer from Enucleated Mesenchymal Stem Cell‐Derived Microvesicles for Chronic Wound Healing

Advanced Science, EarlyView.
This study develops enucleated MSC‐derived microvesicles (Mito@euMVs) to deliver functional mitochondria for optimizing wound repair. By efficiently encapsulating mitochondria, Mito@euMVs rejuvenate hyperglycemia‐induced senescent fibroblasts and HUVECs. Using PVA microneedle patches, the therapeutic efficacy of Mito@euMVs is validated in diabetic rats
Zixuan Dong, Xiaobing Liu, Shichun Li, Xiaoling Fu   +3 more
wiley   +1 more source

STATE OF THE MATRIX METALLOPROTEINASES AND THEIR ROLE IN FORMATION OF THE CHRONIC HEART FAILURE IN CHILDREN WITH DILATED CARDIOMYOPATHY

Педиатрическая фармакология, 2009
The article is devoted to an important section of the pediatric cardiology — dilated cardiomyopathy (DCMP). This is largely due to the spread of the given disease, its possible progress and tendency to the formation of the chronic heart failure (CHF ...
E.N. Basargina, A.G. Gasanov, T.V. Bershova, M.I. Bakanov, A.P. Ivanov, O.O. Kupriyanova   +5 more
doaj  

Matrix metalloproteinase-1 is induced by epidermal growth factor in human bladder tumour cell lines and is detectable in urine of patients with bladder tumours [PDF]

, 1998
J E Nutt, J.K. Mellon, Khaver Qureshi, John Lunec   +3 more
openalex   +1 more source

CCDC80 Protects against Aortic Dissection and Rupture by Maintaining the Contractile Smooth Muscle Cell Phenotype

Advanced Science, EarlyView.
Aortic dissection (AD) is accompanied by a decrease in CCDC80 in vascular smooth muscle cells (VSMCs). CCDC80 can interact with JAK2, and VSMC‐specific CCDC80 deficiency accelerates the progression of AD by activating the JAK2/STAT3 pathway involved in regulating the phenotype switching and function of VSMCs.
Qingqing Xiao, Yi Li, Bin Cai, Xiying Huang, Liang Fang, Feng Liang, Long Chen, Ke Xu, Weifeng Zhang, Xiaolei Wang, Anwen Yin, Xia Wang, Zhaohua Cai, Fei Zhuang, Qin Shao, Bin Zhou, Berthold Hocher, Ben He, Linghong Shen   +18 more
wiley   +1 more source

Matrix metalloproteinases degrade insulin-like growth factor-binding protein-3 in dermal fibroblast cultures.

, 1994
John L. Fowlkes, Jan J. Enghild, Ko Suzuki, Hideaki Nagase   +3 more
openalex   +1 more source

cDNA cloning and expression of bovine procollagen I N-proteinase. A new member of the superfamily of zinc-metalloproteinases with binding sites for cells and other matrix components [PDF]

, 1997
Alain Colige, Shiwu Li, Aleksander L. Sieroń, Betty Nusgens, Darwin J. Prockop, Charles M. Lapierre   +5 more
openalex   +1 more source