Results 31 to 40 of about 4,824 (216)
K-homological finiteness and hyperbolic groups [PDF]
Motivated by classical facts concerning closed manifolds, we introduce a strong finiteness property in K-homology. We say that a C*-algebra has uniformly summable K-homology if all its K-homology classes can be represented by Fredholm modules which are ...
Emerson, Heath, Nica, Bogdan
core +1 more source
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Loop Vertex Expansion for Phi^2k Theory in Zero Dimension
In this paper we extend the method of loop vertex expansion to interactions with degree higher than 4. As an example we provide through this expansion an explicit proof that the free energy of Phi^2k scalar theory in zero dimension is Borel-Le Roy ...
Rivasseau, Vincent, Wang, Zhituo
core +2 more sources
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
A new double series space derived by factorable matrix and four-dimensional matrix transformations
In this study, we introduce a new double series space $ \left\vert F_{a, b}^{u, \theta }\right\vert _{k} $ using the four dimensional factorable matrix $ F $ and absolute summability method for $ k\geq 1 $.
Aslıhan ILIKKAN CEYLAN +1 more
doaj +1 more source
Asymptotic spectral theory for nonlinear time series
We consider asymptotic problems in spectral analysis of stationary causal processes. Limiting distributions of periodograms and smoothed periodogram spectral density estimates are obtained and applications to the spectral domain bootstrap are given ...
Shao, Xiaofeng, Wu, Wei Biao
core +2 more sources
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Ergodic Actions and Spectral Triples [PDF]
In this article, we give a general construction of spectral triples from certain Lie group actions on unital C*-algebras. If the group G is compact and the action is ergodic, we actually obtain a real and finitely summable spectral triple which satisfies
Gabriel, Olivier, Grensing, Martin
core

