Results 81 to 90 of about 21,996,514 (252)

Simplified State Interaction for Matrix Product State Wave Functions. [PDF]

open access: yesJ Chem Theory Comput, 2021
Freitag L   +3 more
europepmc   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Continuous matrix-product operators for quantum fields

open access: yesPhysical Review Research
In this work, we introduce an ansatz for continuous matrix-product operators for quantum field theory. We show that (1) they admit a closed-form expression in terms of finite number of matrix-valued functions without reference to any lattice parameter ...
Erickson Tjoa, J. Ignacio Cirac
doaj   +1 more source

Efficient construction of the Feynman-Vernon influence functional as matrix product states

open access: yesSciPost Physics Core
The time-evolving matrix product operator (TEMPO) method has become a very competitive numerical method for studying the real-time dynamics of quantum impurity problems.
Chu Guo, Ruofan Chen
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Purifications of multipartite states: limitations and constructive methods

open access: yesNew Journal of Physics, 2013
We analyze the description of quantum many-body mixed states using matrix product states and operators. We consider two such descriptions: (i) as a matrix product density operator of bond dimension D ; and (ii) as a purification that is written as a ...
Gemma De las Cuevas   +3 more
doaj   +1 more source

Testing of a Structures Covariance Matrix for Three-Level Repeated Measures Data. [PDF]

open access: yes
This paper considers the problem of estimating, and testing for, a Kronecker product covariance structure of three-level (multiple time points (p), multiple sites (u), and multiple response variables (q)) multivariate data.
Ricardo Leiva, Anuradha Roy
core  

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