Results 111 to 120 of about 303,055 (260)
On rank of a matrix associated with graph
Electronic Notes in Discrete Mathematics, 2000 Abstract In this paper we investigate the upper bound on the smallest number of cliques that cover the vertices of graph G in terms of the rank of a matrix associated with it. Let X be real matrix that is indexed by vertices of G such that all its diagonal entries are non-zero and Xij = 0 whenever vertices i,j are non-adjacent. Then χ (G)≤ 3
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Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
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Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
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The factor width rank of a matrix
Linear Algebra and its Applications23 pages, newly added Theorem ...
Nathaniel Johnston +2 more
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A Designed Thresholding Operator for Low-Rank Matrix Completion
MathematicsIn this paper, a new thresholding operator, namely, designed thresholding operator, is designed to recover the low-rank matrices. With the change of parameter in designed thresholding operator, the designed thresholding operator can apply less bias to ...
Angang Cui, Haizhen He, Hong Yang
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Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
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Hardware-Efficient Optical Matrix Processor via Low-Rank Approximation
IEEE Photonics JournalWe propose a hardware-efficient optical matrix processor based on low-rank approximation, utilizing narrowband filters of microring resonators (MRRs) and broadband Mach-Zehnder interferometers (MZIs).
Weiwei Pan +4 more
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CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
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