Results 81 to 90 of about 302,520 (264)
Handle Matrix Rank Deficiency, Noise, and Interferences in 3D Emission-Excitation Matrices: Effective Truncated Singular-Value Decomposition in Chemometrics Applied to the Analysis of Polycyclic Aromatic Compounds. [PDF]
ACS Omega, 2022 Haouchine M +4 more
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Sharp decrease in the Laplacian matrix rank of phase-space graphs: a potential biomarker in epilepsy. [PDF]
Cogn Neurodyn, 2021 Yang Z, Fan D, Wang Q, Luan G.
europepmc +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
A new method based on the manifold-alternative approximating for low-rank matrix completion
Journal of Inequalities and Applications, 2018 In this paper, a new method is proposed for low-rank matrix completion which is based on the least squares approximating to the known elements in the manifold formed by the singular vectors of the partial singular value decomposition alternatively.
Fujiao Ren, Ruiping Wen
doaj +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Inverting the sum of two singular matrices
Results in Applied MathematicsSquare matrices of the form A˜=A+eDf∗ are considered. An explicit expression for the inverse is given, provided A˜ and D are invertible with rank(A˜)=rank(A)+rank(eDf∗). The inverse is presented in two ways, one that uses singular value decomposition and
Sofia Eriksson, Jonas Nordqvist
doaj +1 more source
Upper Bounds for the Isolation Number of a Matrix over Semirings
Mathematics, 2019 Let S be an antinegative semiring. The rank of an m × n matrix B over S is the minimal integer r such that B is a product of an m × r matrix and an r × n matrix.
LeRoy B. Beasley, Seok-Zun Song
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source