Results 41 to 50 of about 415,107 (313)
Attributed Network Representation Learning Based on Matrix Factorization [PDF]
To combine the information of network topological structure and node attribute to improve the quality of network representation learning,this paper proposes a new attributed network representation learning algorithm,named ANEMF.The algorithm introduces ...
ZHANG Pan, LU Guangyue, Lü Shaoqing, ZHAO Xueli
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Latent Multi-View Semi-Nonnegative Matrix Factorization with Block Diagonal Constraint
Multi-view clustering algorithms based on matrix factorization have gained enormous development in recent years. Although these algorithms have gained impressive results, they typically neglect the spatial structures that the latent data representation ...
Lin Yuan +3 more
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Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Research on splitting quaternions with generalized Tribonacci hybrid number components [PDF]
This paper introduces the Generalized Tribonacci Hybrid Split Quaternion (GTHSQ), a novel split quaternion with coefficients derived from generalized Tribonacci hybrid numbers.
Yanni Yang, Yong Deng
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Matrix Representation of Supersymmetry [PDF]
A matrix representation of the super symmetry is introduced, based on the superfield formulation. The group structure of the finite supertransformations is shown to be closely connected with this representation, and a 16-component covariant derivative is naturally intro duced in this context.
T. Hori, S. Saito
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Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source

