Results 61 to 70 of about 434,585 (264)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

A new thought about the reduction method for tridiagonalizing symmetric indefinite matrices

上海师范大学学报. 自然科学版, 2013
The key problem of achievingPAPT=LTLT for tridiagonalizing symmetric indefinite matrices is how to design the recurrence calculations from Tk-1 to Tk. Direct calculations would lead to a heavy workload. With construction and proof, this paper studies the
SU Er
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Matrix Representation of Virus Machines

Virus machines are unconventional and bio-inspired models of computation based on the transmission of viruses among hosts. Virus machines are known to be computationally complete (they are algorithms), able to solve computationally hard problems. In this work we present a novel matrix representation for virus machines.
Antonio Ramírez-de-Arellano, Francis George C. Cabarle, David Orellana-Martín, Mario J. Pérez-Jiménez, Henry N. Adorna   +4 more
openaire   +2 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Matrix Representation of Capacity-Based Multicriteria Decision Analysis

IEEE Access, 2019
Matrix algebra is an efficient way to represent the relationship between different concepts in the multiple criteria decision analysis theory. The main purpose of this paper is to provide a compact and systematic representation of the capacities and ...
Rui-Jie Xi, Jian-Zhang Wu, Gleb Beliakov
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Enhancement of Vital Signals for UWB Through-Wall Radar Using Low-Rank and Block-Sparse Matrix Decomposition

Remote Sensing
Ultra-wideband (UWB) vital detection radar plays an important role in post-disaster search and rescue, but the vital signal acquired in practice is often submerged in noise.
Xiao Liang, Shengbo Ye, Chenyang Song, Qingyang Kong, Xiaojun Liu, Guangyou Fang   +5 more
doaj   +1 more source

Smooth Non-negative Low-Rank Graph Representation for Clustering [PDF]

Jisuanji kexue yu tansuo
The existing low-rank graph representation algorithms fail to capture the global representation structure of data accurately, and cannot make full use of the valid information of data to guide the construction of the representation graph, then the ...
QIAN Luoxiong, CHEN Mei, ZHANG Chi, ZHANG Jinhong, MA Xueyan
doaj   +1 more source