Results 91 to 100 of about 1,672,356 (290)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Shuttle Program. Euler angles, quaternions, and transformation matrices working relationships [PDF]

A brief mathematical development of the relationship between the Euler angles and the transformation matrix, the quaternion and the transformation matrix, and the Euler angles and the quaternion is presented.
Henderson, D. M.
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Analysis of the algorythms accuracy of the plane and space geodetic coordinates transformation

Geodesy and Cartography, 2012
The accuracy of the coordinates computed by transformation from one system to another is analysed. Values of transformation parameters are computed by the least-square method taking into account the accuracy of the coordinates of the identical points in ...
Jonas Skeivalas, Robertas Dargis
doaj   +1 more source

Algebraic construction of the Darboux matrix revisited

, 2009
We present algebraic construction of Darboux matrices for 1+1-dimensional integrable systems of nonlinear partial differential equations with a special stress on the nonisospectral case.
Arnold W I, Bart H, Belinsky V A, Bobenko A I, Bobenko A I, Bohner M, Boiti M, Boutet de Monvel A, Burtsev S P, Cieśliński J, Cieśliński J L, Cieśliński J L, Cieśliński J L, Cieśliński J L, Coley A, Darboux G, Doktorov E V, Gohberg I, Gu G C, Gu G C, Guest M A, Hoenselaers C, Its A R, Jan L Cieśliński, Krichever I M, Leble S B, Levi D, Matveev V B, Mañas M, Meinel R, Mikhailov A V, Mikhailov A V, Neugebauer G, Nijhoff F, Nimmo J J C, Novikov S P, Oevel W, Pressley A N, Rogers C, Sakhnovich A L, Sakhnovich L A, Sakhnovich L A, Saleem U, Shabat A B, Shin H J, Terng C L, Uhlenbeck K, Zakharov V E, Zakharov V E, Zakharov V E, Zhou Z X   +50 more
core   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Research of Zones of Deficient Profile Gearings of Toothed Belt Drives

Механика машин, механизмов и материалов, 2009
The kinematics of toothed belt drives on the basis of matrix transformation of coordinates is investigated. Analytical dependences of corners of incomplete gearings of toothed from key parameters of drive are received.
A.G. Bakhanovich
doaj  

Random Matrix Transformation and Its Application in Image Hiding. [PDF]

Sensors (Basel), 2023
Wang J, Tan FS, Yuan Y.
europepmc   +1 more source