Results 111 to 120 of about 1,672,356 (290)

K-Means clustering outsourcing scheme based on sparse matrix transformation and bounded random perturbation

Tongxin xuebao
To address the problem that existing secure outsourcing schemes for K-Means clustering incur high computational and communication overhead, making them difficult to satisfy the efficiency requirements of practical applications, a privacy-preserving K ...
Zhao Wei, Tan Jingwen, Wang Huanran, Han Shuai, Yang Wu, Lai Mingzhu   +5 more
doaj  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

A New Perspective on the Average Mixing Matrix

, 2017
We consider the continuous-time quantum walk defined on the adjacency matrix of a graph. At each instant, the walk defines a mixing matrix which is doubly-stochastic. The average of the mixing matrices contains relevant information about the quantum walk
Coutinho, Gabriel, Godsil, Chris, Guo, Krystal, Zhan, Hanmeng   +3 more
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Engineering d-orbital of copper single-atom sites toward industrial-level electrocatalytic methanation

Nature Communications
Copper (Cu)-based single-atom catalysts (SACs) enable electrocatalytic CO2 reduction into methane (CH4) fuel for thermal power plant decarbonization, yet conventional Cu SACs face industrial deployment barriers like instability and sluggish kinetics ...
Zhengzheng Liu, Junzhuo Cai, Shuming Dong, Chaoxiu Qin, Zhuoran Lv, Yu Yang, Jiacheng Jayden Wang, Jiaxu Gong, Huibin Zhang, Huazhen Cao, Anxiang Guan, Zhangliu Tian, Qing Han, Fengwang Li, Fuqiang Huang, Ximeng Lv, Guoqu Zheng   +16 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

A Vision Based Top-View Transformation Model for a Vehicle Parking Assistant

Sensors, 2012
This paper proposes the Top-View Transformation Model for image coordinate transformation, which involves transforming a perspective projection image into its corresponding bird’s eye vision.
Chien-Chuan Lin, Ming-Shi Wang
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Matrix Transformations and Generalized Almost Convergence II

Communications, Faculty Of Science, University of Ankara Series A1Mathematics and Statistics, 1978
Recently M. Stieglitz introduced the concept of Fg -convergence of sequcnce and generalized the results of Eizen and Laush, King, and Shaefer for more general classes of matrices. Quite recently Ahmad and Mursaleen have extended the space Fg of Fg - convergent sequences to Fg (p).
openaire   +5 more sources

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source