Results 111 to 120 of about 3,537,029 (295)

Analysis of G-Transformation Modes for Building Neuro-like Parallel–Hierarchical Network Identification of Rail Surface Defects

Mathematics
This work presents the construction of a transformation for the identification of surface defects on rails, starting with the selection of elements from the matrix and the creation of different matrices. It further elaborates on the recursive formulation
Vaidas Lukoševičius, Volodymyr Tverdomed, Leonid Tymchenko, Natalia Kokriatska, Yurii Didenko, Mariia Demchenko, Olena Oliynyk   +6 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Paradiset och katastrofen – transformation och självtillblivelse genom Tove Janssons Pappan och havet [PDF]

Artikeln utforskar transformation och självtillblivelse i den finländska mång konstnären Tove Janssons (1914-2001) konstnärsvärv med utgångspunkt i sago romanen Pappan och havet publicerad 1965.
Wolf, Helene
core  

Integrable properties and soliton dynamics for the generalized n-component Sasa-Satsuma equation via the Dbar-dressing method

Nuclear Physics B
Based on a (2n+1)×(2n+1) matrix Dbar equation and two linear equations concerning the spectral transformation matrix, the generalized n-component Sasa-Satsuma (GNSS) equation is investigated via the Dbar-dressing method.
Qi Chen, Tao Deng, Chunxia Li, Yuqin Yao
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Research on Modeling and Solving of Shield Tunneling Posture based on Homogeneous Transformation Matrix

Jixie chuandong, 2021
In order to more accurately and quickly solve the shield machine pose change during the tunneling process， a positive solution method for the pose of the shield machine based on the spatial homogeneous transformation matrix element is used to establish a
Qiang Zhang, Dongchen Qin, Peng Zhou, Qiang Zhu, Jiangyi Chen   +4 more
doaj  

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Mass and Stiffness Correlation Using a Transformation Matrix

Infrastructures
Model correlation techniques are methods used to compare two different models, usually a numerical model and an experimental model. According to the structural dynamic modification theory, the experimental mode shapes estimated by modal analysis can be ...
Natalia García Fernández, Pelayo Fernández Fernandez, Rune Brincker, Manuel Aenlle López   +3 more
doaj   +1 more source