Results 111 to 120 of about 2,222,110 (295)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Extension of Mazhar’s theorem on summability factors

Kuwait Journal of Science, 2015
By  (X; Y ) we denote the set of all sequences such thatPa nnis summable  X wheneverPa n is summable Y , where X and Y are sum-mability methods. In this paper we characterize the set  (jC; jk ;N; p n)  fork >  1; > 􀀀1 and arbitrary positive ...
MEHMET ALI SARIGOL
doaj  

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Soliton Solutions to Sasa–Satsuma-Type Modified Korteweg–De Vries Equations by Binary Darboux Transformations

Mathematics
Sasa–Satsuma (SS)-type integrable matrix modified Korteweg–de Vries (mKdV) equations are derived from two group constraints, involving the replacement of the spectral matrix in the Ablowitz–Kaup–Newell–Segur matrix eigenproblems with its matrix transpose
Wen-Xiu Ma
doaj   +1 more source

Matrix Transformations and Disk of Convergence in Interpolation Processes

International Journal of Mathematics and Mathematical Sciences, 2008
Let 𝐴𝜌 denote the set of functions analytic in |𝑧|
Chikkanna R. Selvaraj, Suguna Selvaraj
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Characterizations of a class of matrix transformations

, 2018
One of the important investigations in the theory of summability is that of finding characterizations on an infinite matrix in order that the matrix should transform one sequence into another sequence space.
Junde, Wu, Wei, Chen, Ronglu, Li
core   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

New Integrated and Differentiated Sequence Spaces $\int{b_{p}^{r,s}}$ and $d\,b_{p}^{r,s}$

Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi
In this work, we construct new sequence spaces by combining the integrated and differentiated sequence spaces with the binomial matrix. Firstly, we provide information about basic matters such as sequence spaces and matrix domain. Subsequently we briefly
Kübra Topal
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