Results 31 to 40 of about 82,578 (262)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

On the paranormed binomial sequence spaces

Universal Journal of Mathematics and Applications, 2018
In this paper the sequence spaces $b_0^{r,s}(p)$, $b_c^{r,s}(p)$, $b_{\infty}^{r,s}(p)$ and $b^{r,s}(p)$ which are the generalization of the classical Maddox's paranormed sequence spaces have been introduced and proved that the spaces $b_0^{r,s}(p ...
Ali Köseoğlu, Serkan Demiriz, Hacer Bilgin Ellidokuzoğlu   +2 more
doaj   +1 more source

Applications of uniform boundedness principle to matrix transformations

Karpatsʹkì Matematičnì Publìkacìï, 2023
Using the uniform boundedness principle of Maddox, we characterize matrix transformations from the space $(\ell_{p}) _{T}$ to the spaces $m(\phi )$ and $n(\phi )$ for the case $1\leq p\leq \infty$, which correspond to bounded linear operators.
M.A. Sarıgöl
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Nonnegative Matrix Factorization with Transform Learning [PDF]

2018 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP), 2018
Traditional NMF-based signal decomposition relies on the factorization of spectral data, which is typically computed by means of short-time frequency transform. In this paper we propose to relax the choice of a pre-fixed transform and learn a short-time orthogonal transform together with the factorization.
Dylan Fagot, Herwig Wendt, Cédric Févotte   +2 more
openaire   +3 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

On the Domain of 4-Dimensional Catalan Matrix in the Space of Absolutely Summable Double Sequences

Universal Journal of Mathematics and Applications
The primary objective of this study is to construct a novel double sequence space by utilizing the domain of a 4-dimensional (4D) matrix in the space $\mathcal{L}_u$ of the absolutely summable double sequences defined via the well-known Catalan numbers.
Sezer Erdem, Serkan Demiriz
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

On Some New Normed Narayana Sequence Spaces

Journal of New Theory
In this paper, we first establish the regular matrix $N$ using Narayana numbers. Then, we create new normed sequence spaces $Z(N)$ using the matrix $ N$ and demonstrate that these spaces are linearly isomorphic to $Z$ where $Z\in\{c_0, c, \ell_p, \ell_ ...
Hacer Bilgin Ellidokuzoğlu
doaj   +1 more source