Results 41 to 50 of about 628,164 (291)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Applications of uniform boundedness principle to matrix transformations

Karpatsʹkì Matematičnì Publìkacìï, 2023
Using the uniform boundedness principle of Maddox, we characterize matrix transformations from the space $(\ell_{p}) _{T}$ to the spaces $m(\phi )$ and $n(\phi )$ for the case $1\leq p\leq \infty$, which correspond to bounded linear operators.
M.A. Sarıgöl
doaj   +1 more source

Supersymmetric transformations for coupled channels with threshold differences

, 2007
The asymptotic behaviour of the superpotential of general SUSY transformations for a coupled-channel Hamiltonian with different thresholds is analyzed.
Aref'eva I, Baye D, Boris F Samsonov, Cannata F, Chadan K, Cooper F, Daniel Baye, Jean-Marc Sparenberg, Kohlhoff H, Newton R G, Samsonov B F, Samsonov B F, Sparenberg J-M, Sukumar C V, Taylor J R   +14 more
core   +2 more sources

Unconstrained optimal transformation matrix [PDF]

IEEE Transactions on Aerospace and Electronic Systems, 1998
We generalize Brock's minimization of the loss function proposed by Wahba to give a least-squares estimate of satellite attitude. We follow Brock in relaxing Wahba's requirement that the minimizing attitude matrix be orthogonal, and discuss the statistical properties of our new solution and its relation to existing attitude estimation algorithms.
F.L. Markley, I.Y. Bar-Itzhack
openaire   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

On the Domain of 4-Dimensional Catalan Matrix in the Space of Absolutely Summable Double Sequences

Universal Journal of Mathematics and Applications
The primary objective of this study is to construct a novel double sequence space by utilizing the domain of a 4-dimensional (4D) matrix in the space $\mathcal{L}_u$ of the absolutely summable double sequences defined via the well-known Catalan numbers.
Sezer Erdem, Serkan Demiriz
doaj   +1 more source

Separation of Coupled Systems of Schrodinger Equations by Darboux transformations

, 2011
Darboux transformations in one independent variable have found numerous applications in various field of mathematics and physics. In this paper we show that the extension of these transformations to two dimensions can be used to decouple systems of ...
Magri F., MAYER HUMI, Nabiev A. A., Rogers C.   +3 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

On Some New Normed Narayana Sequence Spaces

Journal of New Theory
In this paper, we first establish the regular matrix $N$ using Narayana numbers. Then, we create new normed sequence spaces $Z(N)$ using the matrix $ N$ and demonstrate that these spaces are linearly isomorphic to $Z$ where $Z\in\{c_0, c, \ell_p, \ell_ ...
Hacer Bilgin Ellidokuzoğlu
doaj   +1 more source