Results 61 to 70 of about 628,164 (291)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Matrix Orientifolding and Models with Four or Eight Supercharges

, 2005
The conditions under which matrix orientifolding and supersymmetry transformations commute are known to be stringent. Here we present the cases possessing four or eight supercharges upon ${\bf Z}_3$ orbifolding followed by matrix orientifolding.
H. Itoyama, H. Itoyama, R. Yoshioka
core   +3 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

On the Matrix Domain in the Sequence Lu [PDF]

Eurasian Journal of Science and Engineering, 2017
In this paper, I introduce a new sequence space as Lu the domain of four dimensional generalized difference matrix(r, s, t , u ) and as a generalization of the series space BV. I give some topological properties with some inclusion relations. Moreover, I
Orhan Tuğ
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Matrix transformations of some sequence spaces [PDF]

Pacific Journal of Mathematics, 1969
This paper is a continuation of [1]. We begin with the notations for the sequence spaces considered in this paper. Let Γ be the space of sequences x = {xp} of complex numbers such that |xp|1/p⃗0 as p⃗∞. Γ can also be regarded as the space of integral functions f(z) = .
openaire   +6 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

On topological properties of spaces obtained by the double band matrix

Open Mathematics, 2017
Let λ denote any one of the spaces ℓ∞ and ℓp and λ(Ť) be the domain of the band matrix Ť. We study ℓp(Ť) for 1 ≤ p ≤ ∞ and give some inclusions and its topological properties.
Zeren Suzan, Bektaş Çiğdem
doaj   +1 more source

Matrices in computer graphics

Tehnički Glasnik, 2018
In this article, the usage of matrices and matrix operations in computer graphics is shown. A brief overview of geometric transformations in computer graphics is given.
Nataša Lončarić, Damira Keček, Marko Kraljić   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source