Results 71 to 80 of about 2,222,110 (295)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Matrix transformations related to I-convergent sequences [PDF]
, 2019 Characterized are matrix transformations related to certain subsets of the space of ideal convergent sequences. Obtained here results are connected with the previous investigations of the author on some transformations defined by infinite matrices of ...
Kolk, Enno
core +1 more source
On topological properties of spaces obtained by the double band matrix
Open Mathematics, 2017 Let λ denote any one of the spaces ℓ∞ and ℓp and λ(Ť) be the domain of the band matrix Ť. We study ℓp(Ť) for 1 ≤ p ≤ ∞ and give some inclusions and its topological properties.
Zeren Suzan, Bektaş Çiğdem
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Predicting directed links using nondiagonal matrix decompositions
, 2012 We present a method for trust prediction based on nondiagonal decompositions of the asymmetric adjacency matrix of a directed network. The method we propose is based on a nondiagonal decomposition into directed components (DEDICOM), which we use to learn
Jorg Fliege +3 more
core +1 more source
Program transformations using temporal logic side conditions [PDF]
, 2009 This paper describes an approach to program optimisation based on transformations, where temporal logic is used to specify side conditions, and strategies are created which expand the repertoire of transformations and provide a suitable level of ...
Richard Warburton +7 more
core +1 more source
Tehnički Glasnik, 2018 In this article, the usage of matrices and matrix operations in computer graphics is shown. A brief overview of geometric transformations in computer graphics is given.
Nataša Lončarić +2 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source