Results 81 to 90 of about 434,628 (281)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

On the finite Fourier transforms of functions with infinite discontinuities

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2002
The introductory part of the paper is provided to give a brief review of the stability theory of a matrix pencil for discrete linear time-invariant singular control systems, based on the causal relationship between Jordan's theorem from the theory of ...
Branko Saric
doaj   +1 more source

Computing Biquadratic Transformation Matrix [PDF]

open access: yesJournal of Institute of Control, Robotics and Systems, 2009
Recently it has been shown in the literature that a biquadratic transformation can be used to deal with the pathological cases arising in the bilinear transformation. This paper concerns the computational aspect of the biquadratic transformation. Two efficient algorithms are presented to compute the transformation matrix.
openaire   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Mathematical transforms and image compression: A review [PDF]

open access: yesMaejo International Journal of Science and Technology, 2010
It is well known that images, often used in a variety of computer and other scientific and engineering applications, are difficult to store and transmit due to their sizes.
Satish K. Singh
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Polynomial approach for the most general linear Fredholm integrodifferential-difference equations using Taylor matrix method

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2006
A Taylor matrix method is developed to find an approximate solution of the most general linear Fredholm integrodifferential-difference equations with variable coefficients under the mixed conditions in terms of Taylor polynomials.
Mehmet Sezer, Mustafa Gülsu
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

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