Results 171 to 180 of about 10,032,286 (342)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Hemispheric Asymmetry in the Genetic Overlap between Schizophrenia and White Matter Microstructure. [PDF]
Zhang Y +17 more
europepmc +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Molecular and Transcriptional Signatures of Gray Matter Volume Alterations Associated With Depressive Symptoms in Mild Cognitive Impairment. [PDF]
Xu H +9 more
europepmc +1 more source
For the second time, the Data Science Challenge took place as part of the 18th symposium “Database Systems for Business, Technology and Web” (BTW) of the Gesellschaft für Informatik (GI). The Challenge was organized by the University of Rostock and sponsored by IBM and SAP.
Meyer, Holger J. +15 more
openaire +1 more source
Ursula Peters, Das Ich im Bild. Die Figur des Autors in volkssprachigen Bilderhandschriften des 13. bis 16. Jahrhunderts. 2008 [PDF]
Matter, Stefan
core
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source

