Results 171 to 180 of about 4,103,257 (286)

Brain edema progression rate on serial CT predicts neurological outcome after cardiac arrest: a region-specific biomarker of hypoxic-ischemic brain injury. [PDF]

Resusc Plus
Xu N, Cheong H, De Z, Li X, Wang Y, Zeng X, Du L.   +6 more
europepmc   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Varied Mulching Practices Modulate Soil Hydrothermal-Nutrient Regimes and Root Yield of Indigowoad Root in an Oasis. [PDF]

Plants (Basel)
Zhou P, Wang Z, Wang Y, Li F, Li X, Huang C, Lei L.   +6 more
europepmc   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Perinatal Brain Injuries in Preterm Infants. [PDF]

Cells
Papazovska Cherepnalkovski A, Brajkovic L, Cogelja K, Milostic LK, Vidovic N, Renic A, Bulat D, Sabljic J, Batinovic E, Bucat M.   +9 more
europepmc   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Marine primary production enhances removal of hydrophobic organic contaminants from Eurasian Arctic shelf waters. [PDF]

Nat Commun
Shi X, Oziel L, Benskin JP, Gustafsson Ö, Sobek A.   +4 more
europepmc   +1 more source

Back Matter Vol. 9 No. 1, 2025

Back Matter Vol. 9 No.
Back Matter
core  

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Novel Protein Ingredients Alter Feed Intake, Digestibility and Faecal Stability in Atlantic Salmon (<i>Salmo salar</i>). [PDF]

Aquac Nutr
Bogevik AS, Meriac A, Ballance S, Samuelsen TA, Aas TS, Alvestad R.   +5 more
europepmc   +1 more source