Results 191 to 200 of about 4,103,257 (286)

The Things That Matter

Design Issues, 1998
Verbeek, Peter P.C.C., Kockelkoren, P.J.H.   +1 more
openaire   +3 more sources

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Technical development and implementation of 3D-QALAS on a 1.5T MR-Linac for the brain: A prospective R-IDEAL stage 0/1 technology development report. [PDF]

J Appl Clin Med Phys
McCullum L, Harrington A, West N, Nehring G, Fu Z, Subashi E, Taylor BA, Hwang KP, Fuller CD.   +8 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Gray matter alterations and their atlas-based spatial associations with neurotransmitter distributions in isolated REM sleep behavior disorder. [PDF]

Sleep Breath
Byun JI, Song H, Shin JH, Kim HJ, Shin WC, Sohn CH, Jung KY.   +6 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Oxygen-enhanced brain MRI using dynamic gradient-echo and MR fingerprinting. [PDF]

Eur Radiol Exp
Fushimi Y, Okuchi S, Utsunomiya Y, Nakajima S, Sakata A, Yamamoto T, Oshima S, Liao C, Imai H, Nakamoto Y.   +9 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source