Results 71 to 80 of about 10,032,286 (342)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Thomas Aquinas, Hylomorphism, and Identity Over Time

open access: yesNoctua, 2016
Identity-Over-Time has been a favorite subject in the literature concerning Thomas Aquinas. Aquinas addresses this issue in many discussions, including especially the identity of material things and artifacts, the identity of the human soul after the ...
Fabrizio Amerini
doaj   +1 more source

Strongly Interacting Matter at High Energy Density [PDF]

open access: yes, 2008
This lecture concerns the properties of strongly interacting matter (which is described by Quantum Chromodynamics) at very high energy density. I review the properties of matter at high temperature, discussing the deconfinement phase transition . At high
McLerran, Larry
core   +3 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

On the concepts of time, space, vacuum and domain of investigation among contemporary physics, philosophy and theological reflection [PDF]

open access: yesPizhūhish/hā-yi Falsafī- Kalāmī
Contemporary theology is realizing the importance of integrating the knowledge ofmodern/contemporary physics into the metaphysical and ontological categories usedto consider God and the God-world relationship.
Paolo Di Sia
doaj   +1 more source

Gravitational effects of condensate dark matter on compact stellar objects

open access: yes, 2012
We study the gravitational effect of non-self-annihilating dark matter on compact stellar objects. The self-interaction of condensate dark matter can give high accretion rate of dark matter onto stars.
Cheng, K. S., Li, Xinyu, Wang, Fayin
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Cosmological implications of a Dark Matter self-interaction energy density

open access: yes, 2010
We investigate cosmological constraints on an energy density contribution of elastic dark matter self-interactions characterized by the mass of the exchange particle and coupling constant.
C. Boehm   +3 more
core   +1 more source

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