Results 71 to 80 of about 9,069,057 (289)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The annihilation cross section of dark matter which is driven by scalar unparticle

, 2013
We analyze the annihilation cross section of dark matter which interacts with the standard model sector over the scalar unparticle propagator. We observe that the annihilation cross section of dark matter pair is sensitive to the dark matter mass and the
Iltan, E. O.
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Les rapports de l’art abstrait (Kandinsky, Klee, Mondrian) avec les tendances d’abstraction de l’art sacré / The Connections of Abstract Art (Kandinsky, Klee, Mondrian) with the Abstractization Tendencies of Sacred Art [PDF]

Anastasis: Research in Medieval Culture and Art, 2016
The main purpose of this paper is to study the connections that can be established between the modern abstractionism and the abstract tendencies from other historical eras.
Gabriel Badea
doaj  

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

A new window on Strange Quark Matter as the ground state of strongly interacting matter

, 2003
If strange quark matter is the true ground state of matter, it must have lower energy than nuclear matter. Simultaneously, two-flavour quark matter must have higher energy than nuclear matter, for otherwise the latter would convert to the former. We show,
A. Gocksch, A. Manohar, C. Alcock, D. Diakonov, D. Diakonov, Dipankar Bhattacharya, E. Farhi, E. Witten, G. Baym, J. Stern, J. Stern, J.A. McGovern, M. Alford, M. Alford, M. Kutschera, M.C. Birse, M.C. Birse, R. Johnson, S. Kahana, V. Soni, V. Soni, Vikram Soni   +21 more
core   +2 more sources

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Ejercicio práctico: "Estaciones para el estudio de la materia"

Investigación y Postgrado, 2004
Con el propósito de lograr una mayor comprensión de toda la dinámica de cambios que ocurren en la naturaleza, se ha implementado el ejercicio práctico "Estaciones para el Estudio de la Materia". Esta estrategia didáctica fue aplicada a una muestra de 152
Alina Isabel María De Jesús Vieira, Rosa Elena Camero   +1 more
doaj  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Space and Matter in the Poetic and Artistic Perception of José Ángel Valente

Castilla: Estudios de Literatura, 2015
The poetry of José Ángel Valente brings up fundamental issues of space and matter, combining the poetic voice with the artistic and philosophical thought.
Ching Yu Lin
doaj