Results 91 to 100 of about 1,708,170 (337)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Improving neonatal health in Nepal: Major challenges to achieving millennium development goal 4 [PDF]

, 2013
Background: Globally, more than 40% of all under-five child deaths occur during the neonatal period. Neonatal mortality in Nepal is 33 per 1,000 live births, eight times that of developed regions.
Joshi, R., Sharma, Sheetal, van Teijlingen, Edwin   +2 more
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Current trends in the use of residential child care in Scotland [PDF]

, 2006
The survey was planned to examine how local authority residential care units were currently being used and to provide data relating to current issues in the use of residential child care. These issues were identified by Scottish Institute for Residential
Hunter, L., Kendrick, A., Milligan, I.M.
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Does Continuity Of Care Matter? [PDF]

Value in Health, 2013
Bermingham, S., Chambers, A., Krahn, M.D.   +2 more
openaire   +2 more sources

Comfort First: Development and pilot testing of a web-based video training to disseminate Comfort Matters dementia care. [PDF]

J Am Geriatr Soc, 2023
Hanson LC, Meeks N, Guo J, Alonzo TRM, Mitchell KM, Gallagher M, Toles M, Harder B, Zimmerman S.   +8 more
europepmc   +1 more source

Collaborative Ethnography and Matters of Care in Counterspaces

Engaging Science, Technology, and Society
This paper offers a reflexive analysis of an interdisciplinary and cross-race collaboration to advance equity in engineering called LATTICE (Launching Academics on the Tenure-Track: an Intentional Community in Engineering).
Coleen Carrigan, Joyce Yen, Cara Margherio, Christine Grant, Claire Horner-Devine, Eve Riskin, Julie Ivy, Burren Peil   +7 more
doaj   +1 more source

Point of care ultrasound training needs for primary care physicians: Practice setting matters

Cogent Education, 2019
Background: Point of care ultrasound (POCUS) is increasingly used in primary care. This study seeks to determine the educational needs of primary care physicians. Methods: All primary care practitioners in Calgary, Alberta, on the electronic departmental
Rabiya Jalil, Robert Warren, Irene W.Y. Ma   +2 more
doaj   +1 more source

Digital technology providing real time feedback about what matters most to patients: lessons learnt and moving forward

International Journal of Integrated Care, 2019
Introduction: The NSW Agency for Clinical Innovation (ACI) recently completed an e-enabled proof-of-concept Patient Reported Measures (PRMs) program.
Melissa Tinsley
doaj   +1 more source