Results 131 to 140 of about 1,708,170 (337)

The Birth Control Divide : U. S. Press Coverage of Contraception, 1873-2013 [PDF]

, 2016
For more than 140 years, religious, medical, legislative, and legal institutions have contested the issue of contraception. In this conversation, predominantly male voices have attached reproductive rights to tangential moral and political matters ...
Garner, Ana C., Michel, Angela
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

The ubiquity of ‘self-care’ in health: Why specificity matters

Global Public Health
Despite increased interest in self-care for health, little consensus exists around its definition and scope. The World Health Organization has published several definitions of self-care, including in a 2019 Global Guideline rooted in sexual and ...
Laura Ferguson, Michelle E. Anderson, Krishni Satchi, Alexander M. Capron, Charles D. Kaplan, Peter Redfield, Sofia Gruskin   +6 more
doaj   +1 more source

International portfolio diversification: Do industry factors dominate country factors?. [PDF]

Despite recent reports to the contrary, we find that even recently-the 1991-2000 period-the country factor still dominates industry influences. This conclusion is robust to different test formats although the relative magnitude of the two sources of ...
De Moor, Lieven, Sercu, Piet
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Learning and leading in the experience age

Patient Experience Journal, 2017
A focus on experiences of care helps health systems realize the very transformations they look to achieve. This is because patient experience allows patients, families and carers to define value, enabling healthcare organizations to focus on what matters
Jane Cummings
doaj  

Advancing a new model of collaborative practice: a decade of Whole Health interprofessional education across Veterans Health Administration

BMC Medical Education
Large-scale implementation of interprofessional education across the United States Veterans Health Administration has supported advancement of a new model of collaborative practice, the Whole Health System, centering on the patient and what matters most ...
Theresa H. Liao, J. Adam Rindfleisch, Kelly Peyton Howard, Marc Castellani, Sara Grimsgaard Noyes   +4 more
doaj   +1 more source

Thinking with Maria Puig de la Bellacasa’s Matters of Care: Concerns, Care, and Justice

Youth
Social justice has become the panacea for all types of concerns and issues—providing a sense that all concerns are worthwhile, comprehensive, and matter for today’s world.
Fernando Santos, Marta Ferreira, Aldina Sofia Silva, Inês Gonçalves   +3 more
doaj   +1 more source

'Getting back to the matters': Why the existential matters in care.

Scandinavian Journal of Caring Sciences, 2021
Kathleen Galvin
semanticscholar   +1 more source