Results 121 to 130 of about 1,708,170 (337)
Inside the Corporate Veil: The Character and Consequences of Executives’ Duties [PDF]
, 2006 This paper is based on a keynote address to the 2006 annual workshop of the Australian Corporate Law Teachers\u27 Association on The Pathology of Corporate Law.
Ljungström, Carl, Nilsson, Anna
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
What Matters? Palliative Care, Ethics, and the COVID-19 Pandemic. [PDF]
J Bioeth Inq, 2020 Sheahan L, Brennan F.
europepmc +1 more source
“What Matters to You?”: A pilot project for implementing patient-centered care
Patient Experience Journal, 2016 This project was intended to enhance the delivery of patient-centered care by asking patients what matters to them before and after total joint replacement (TJR) surgery.
Anthony DiGIoia +2 more
doaj
How Has ‘What Matters to You’ Been Used for Patient Care? A Scoping Review
Health ExpectationsIntroduction Asking patients ‘What matters to you?’ (WMTY) was first introduced in 2012 as an approach to person‐centred care and has since been integrated into healthcare frameworks internationally.
Carrie Janerka +3 more
doaj +1 more source
Mortality matters: providing a universal ground for care
International Journal of Ageing and Later LifeCan centering mortality contribute to a caring society? My argument in this paper is that while analyzing the intersections of oppression matters, highlighting the universal need for care also matters. This common ground has been hidden.
Albert Banerjee
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source