Results 101 to 110 of about 895,186 (317)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Use of homologous and heterologous gene expression profiling tools to characterize transcription dynamics during apple fruit maturation and ripening [PDF]

, 2010
Background Fruit development, maturation and ripening consists of a complex series of biochemical and physiological changes that in climacteric fruits, including apple and tomato, are coordinated by the gaseous hormone ethylene.
Valeria Soglio, Schouten, H.J., Fei, Zhangjun, Schouten, Henk, MUSACCHI, STEFANO, S. Sansavini, Henk Schouten, H. Schouten, Costa, G., Alba, Rob, Schouten, H., Serra, S., Alba Rob, S. Musacchi, Serra Sara, Costa Fabrizio, Alba, R., Guglielmo Costa, G. Costa, Sansavini Silviero, Sansavini, S., Soglio Valeria, Sara Serra, Soglio, Valeria, Fei, Z. J., Schouten Henk, Giovannoni, J., Soglio, V., Costa, Fabrizio, Costa Guglielmo, James Giovannoni, Gianfranceschi Luca, Silviero Sansavini, Costa, Guglielmo, Giovannoni James, Stefano Musacchi, Zhangjun Fei, SANSAVINI, SILVIERO, L. Gianfranceschi, SERRA, SARA, Gianfranceschi, Luca, Gianfranceschi, L., J. Giovannoni, Fei, Z., Fei Zhangjun, Giovannoni, James, Musacchi Stefano, Costa, F., V. Soglio, F. Costa, R. Alba, Z. Fei, Rob Alba, S. Serra, Musacchi, S., Fabrizio Costa, Luca Gianfranceschi   +56 more
core   +1 more source

The Role of the Coat Protein A-Domain in P22 Bacteriophage Maturation

Viruses, 2014
Bacteriophage P22 has long been considered a hallmark model for virus assembly and maturation. Repurposing of P22 and other similar virus structures for nanotechnology and nanomedicine has reinvigorated the need to further understand the protein-protein ...
David S. Morris, Peter E. Prevelige
doaj   +1 more source

The maturation of Eurosurveillance

Eurosurveillance, 2000
The recent union of the monthly bulletin Eurosurveillance and its all-electronic sister Eurosurveillance Weekly into a unique project marked the start of a new stage in their development.
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Temporal progression in migratory status and sexual maturation in European silver eels during downstream migration [PDF]

, 2011
The onset of downstream migration of European eels is accompanied by a cessation of feeding and the start of sexual maturation which stresses the link between metabolism and sexual maturation, also suggesting an important role for exercise.
Guerrero, M.A., Gerard de Laak, Thillart, G.E.E.J.M., Ma. Angeles Guerrero, Guido E. E. J. M. van den Thillart, Arjan P. Palstra, Jan P. G. Klein Breteler, Palstra, A.P., Klein Breteler, J.G.P.   +8 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Participação do fator de crescimento fibroblástico 18 (FGF18) na maturação nuclear oocitária, expansão das células do cumulus e produção in vitro de embriões bovinos [PDF]

, 2015
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Biologia Celular e do Desenvolvimento, Florianópolis, 2015.Este trabalho propôs estudar a ação do Fator de Crescimento ...
Silva, Yago Pinto da
core  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source