Results 91 to 100 of about 895,186 (317)

In vitro Chicken Bone Marrow-Derived Dendritic Cells Comprise Subsets at Different States of Maturation

open access: yesFrontiers in Immunology, 2020
Research in chickens has been fundamental for the discovery of basic aspects of the immune system and has led to an interest in the in-depth characterization of avian immune cell types including dendritic cells (DCs).
Robin H. G. A. van den Biggelaar   +5 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Preoperative Calcium-Phosphorus Status and Arteriovenous Fistula Maturation [PDF]

open access: yes
Introduction: Although arteriovenous fistula (AVF) is the preferred vascular access in hemodialysis (HD) practice, AVF maturation is a common issue.
Cihan Uysal   +4 more
core   +1 more source

Engineering Scalable Manufacturing of High-Quality Stem Cell-Derived Cardiomyocytes for Cardiac Tissue Repair

open access: yesFrontiers in Medicine, 2018
Recent advances in the differentiation and production of human pluripotent stem cell (hPSC)-derived cardiomyocytes (CMs) have stimulated development of strategies to use these cells in human cardiac regenerative therapies.
Kaitlin K. Dunn, Sean P. Palecek
doaj   +1 more source

The psychology of bio-banding: a Vygotskian perspective

open access: yesAnnals of Human Biology, 2020
Context Bio-banding is the process of grouping players by their maturational status rather than chronological age. It is designed to limit the impact of maturational timing on talent identification and development and expose early and late maturing ...
Megan Hill   +5 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

SinCMat: A single-cell-based method for predicting functional maturation transcription factors [PDF]

open access: yes
peer reviewedA major goal of regenerative medicine is to generate tissue-specific mature and functional cells. However, current cell engineering protocols are still unable to systematically produce fully mature functional cells.
OKAWA, Satoshi   +2 more
core   +1 more source

Heterogeneity in thymic emigrants: implications for thymectomy and immunosenescence. [PDF]

open access: yes, 2013
The development of mature, antigen-inexperienced (naive) T cells begins in the thymus and continues after export into the periphery. Post-thymic maturation of naive T cells, in humans, coincides with the progressive loss of markers such as protein ...
Iren Bains (382649)   +11 more
core   +1 more source

Experience-Dependent Equilibration of AMPAR-Mediated Synaptic Transmission during the Critical Period

open access: yesCell Reports, 2017
Experience-dependent synapse refinement is essential for functional optimization of neural circuits. However, how sensory experience sculpts excitatory synaptic transmission is poorly understood.
Kyung-Seok Han   +2 more
doaj   +1 more source

Mature [PDF]

open access: yesJournal of Thrombosis and Haemostasis, 2015
F R, Rosendaal, P H, Reitsma
openaire   +2 more sources

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