Results 1 to 10 of about 157,187 (261)

RF_phage virion: Classification of phage virion proteins with a random forest model

open access: yesFrontiers in Genetics, 2023
Introduction: Phages play essential roles in biological procession, and the virion proteins encoded by the phage genome constitute critical elements of the assembled phage particle.Methods: This study uses machine learning methods to classify phage ...
Yanqin Zhang, Zhiyuan Li
doaj   +3 more sources

Study of a tick-borne encephalitis vaccine

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2023
Scientific relevance. Tick-borne encephalitis is one of the most significant anthropozoonoses   for public health in the Russian Federation. Wide vaccination coverage is required to control  this zoonotic infection.
O. V. Stronin   +2 more
doaj   +1 more source

Noroviruses—The State of the Art, Nearly Fifty Years after Their Initial Discovery

open access: yesViruses, 2021
Human noroviruses are recognised as the major global cause of viral gastroenteritis. Here, we provide an overview of notable advances in norovirus research and provide a short recap of the novel model systems to which much of the recent progress is owed.
Louisa F. Ludwig-Begall   +2 more
doaj   +1 more source

Influence of Different Glycoproteins and of the Virion Core on SERINC5 Antiviral Activity

open access: yesViruses, 2021
Host plasma membrane protein SERINC5 is incorporated into budding retrovirus particles where it blocks subsequent entry into susceptible target cells.
William E. Diehl   +6 more
doaj   +1 more source

Dynamics of dust particles with virions in gas cloud [PDF]

open access: yesE3S Web of Conferences, 2023
The relevance is due to the lack of study and development of models of the movement of virions under the action of gravitational and dissipative components in the Earth's atmosphere. The article presents the results of modeling the movement of virions in
Volnikov Mikhail
doaj   +1 more source

Re-Discovery of Giardiavirus: Genomic and Functional Analysis of Viruses from Giardia duodenalis Isolates

open access: yesBiomedicines, 2021
Giardiasis, caused by the protozoan parasite Giardia duodenalis, is an intestinal diarrheal disease affecting almost one billion people worldwide. A small endosymbiotic dsRNA viruses, G.
Gianluca Marucci   +10 more
doaj   +1 more source

A tail-like assembly at the portal vertex in intact herpes simplex type-1 virions [PDF]

open access: yes, 2012
Herpes viruses are prevalent and well characterized human pathogens. Despite extensive study, much remains to be learned about the structure of the genome packaging and release machinery in the capsids of these large and complex double-stranded DNA ...
Corey W. Hecksel   +6 more
core   +12 more sources

Hepatitis B virus polymerase-specific T cell epitopes shift in a mouse model of chronic infection

open access: yesVirology Journal, 2021
Background Chronic hepatitis B virus (HBV) infection (CHB) is a significant public health problem that could benefit from treatment with immunomodulators. Here we describe a set of therapeutic HBV vaccines that target the internal viral proteins. Methods
Mohadeseh Hasanpourghadi   +6 more
doaj   +1 more source

An alphaherpesvirus exploits antimicrobial beta-defensins to initiate respiratory tract infection [PDF]

open access: yes, 2020
beta-Defensins protect the respiratory tract against the myriad of microbial pathogens entering the airways with each breath. However, this potentially hostile environment is known to serve as a portal of entry for herpesviruses.
Boyen, Filip   +8 more
core   +2 more sources

Direct and dynamic detection of HIV-1 in living cells. [PDF]

open access: yes, 2012
In basic and applied HIV research, reliable detection of viral components is crucial to monitor progression of infection. While it is routine to detect structural viral proteins in vitro for diagnostic purposes, it previously remained impossible to ...
Helma, Jonas   +7 more
core   +8 more sources

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