Results 11 to 20 of about 104,970 (255)

From Crescent to Mature Virion: Vaccinia Virus Assembly and Maturation

open access: yesViruses, 2014
Vaccinia virus (VACV) has achieved unprecedented success as a live viral vaccine for smallpox which mitigated eradication of the disease. Vaccinia virus has a complex virion morphology and recent advances have been made to answer some of the key ...
Paul Howley, John D Hayball, Liang Liu
exaly   +3 more sources

Study of a tick-borne encephalitis vaccine

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2023
Scientific relevance. Tick-borne encephalitis is one of the most significant anthropozoonoses   for public health in the Russian Federation. Wide vaccination coverage is required to control  this zoonotic infection.
O. V. Stronin   +2 more
doaj   +1 more source

Noroviruses—The State of the Art, Nearly Fifty Years after Their Initial Discovery

open access: yesViruses, 2021
Human noroviruses are recognised as the major global cause of viral gastroenteritis. Here, we provide an overview of notable advances in norovirus research and provide a short recap of the novel model systems to which much of the recent progress is owed.
Louisa F. Ludwig-Begall   +2 more
doaj   +1 more source

Re-Discovery of Giardiavirus: Genomic and Functional Analysis of Viruses from Giardia duodenalis Isolates

open access: yesBiomedicines, 2021
Giardiasis, caused by the protozoan parasite Giardia duodenalis, is an intestinal diarrheal disease affecting almost one billion people worldwide. A small endosymbiotic dsRNA viruses, G.
Gianluca Marucci   +10 more
doaj   +1 more source

Dynamics of dust particles with virions in gas cloud [PDF]

open access: yesE3S Web of Conferences, 2023
The relevance is due to the lack of study and development of models of the movement of virions under the action of gravitational and dissipative components in the Earth's atmosphere. The article presents the results of modeling the movement of virions in
Volnikov Mikhail
doaj   +1 more source

Hepatitis B virus polymerase-specific T cell epitopes shift in a mouse model of chronic infection

open access: yesVirology Journal, 2021
Background Chronic hepatitis B virus (HBV) infection (CHB) is a significant public health problem that could benefit from treatment with immunomodulators. Here we describe a set of therapeutic HBV vaccines that target the internal viral proteins. Methods
Mohadeseh Hasanpourghadi   +6 more
doaj   +1 more source

Multiscale Modeling of an 8-Week Combination Regimen of Bemnifosbuvir and Ruzasvir in Patients with Chronic Hepatitis C Virus Infection. [PDF]

open access: yesClin Pharmacol Ther
Bemnifosbuvir (BEM) and ruzasvir (RZR) are pan‐genotypic HCV polymerase (NS5B) and NS5A inhibitors, respectively. In a single‐arm study (NCT05904470), 215 treatment‐naïve, adherent participants with chronic HCV (with or without cirrhosis) received BEM 550 mg QD plus RZR 180 mg QD for 8 weeks.
Zitzmann C   +4 more
europepmc   +2 more sources

Defective Virions of Reovirus [PDF]

open access: yesJournal of Virology, 1970
When purified preparations of stock reovirus, type 3, were digested with chymotrypsin, the virions were converted into two different types of particle. These new particles could be separated from each other by isopycnic centrifugation in cesium chloride gradients. One particle banded at a buoyant density of 1.43 g/cm 3
M, Nonoyama, Y, Watanabe, A F, Graham
openaire   +2 more sources

Inhibitory effect of gamma irradiation against Cucumber green mottle mosaic virus

open access: yesPlant Protection Science, 2017
Gamma irradiation has been shown to be an effective method of controlling plant bacterial and fungal pathogens, but data on its effect against plant viruses is limited.
Jin-Sung Hong   +2 more
doaj   +1 more source

Predominant secondary dengue infection among Vietnamese adults mostly without warning signs and severe disease

open access: yesInternational Journal of Infectious Diseases, 2020
Background: The morbidity in dengue fever is dependent on the dengue virus (DENV) serotypes, the patient age, predisposing immunogenic markers and the frequency of primary and secondary infections.
Simon D. Lytton   +13 more
doaj   +1 more source

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